Literature DB >> 28785460

Impact of Exercise Training on Peak Oxygen Uptake and its Determinants in Heart Failure with Preserved Ejection Fraction.

Wesley J Tucker1, Michael D Nelson1, Rhys I Beaudry1, Martin Halle2, Satyam Sarma3,4, Dalane W Kitzman5, Andre La Gerche6, Mark J Haykowksy1,6.   

Abstract

Heart failure with preserved ejection (HFpEF) accounts for over 50 % of all HF cases, and the proportion is higher among women and older individuals. A hallmark feature of HFpEF is dyspnoea on exertion and reduced peak aerobic power (VO2peak) secondary to central and peripheral abnormalities that result in reduced oxygen delivery to and/or utilisation by exercising skeletal muscle. The purpose of this brief review is to discuss the role of exercise training to improve VO2peak and the central and peripheral adaptations that reduce symptoms following physical conditioning in patients with HFpEF.

Entities:  

Keywords:  Heart failure with preserved ejection fraction; exercise training; peak aerobic power

Year:  2016        PMID： 28785460      PMCID： PMC5490876          DOI： 10.15420/cfr.2016:16:2

Source DB:  PubMed          Journal:  Card Fail Rev        ISSN： 2057-7540


  65 in total

Review 1.  Vascular Dysfunction in Heart Failure with Preserved Ejection Fraction.

Authors:  Dalane W Kitzman; Mark J Haykowsky
Journal:  J Card Fail       Date:  2015-11-14       Impact factor: 5.712

2.  Effects of dietary nitrate on oxygen cost during exercise.

Authors:  F J Larsen; E Weitzberg; J O Lundberg; B Ekblom
Journal:  Acta Physiol (Oxf)       Date:  2007-07-17       Impact factor: 6.311

Review 3.  Heart failure with preserved ejection fraction: mechanisms, clinical features, and therapies.

Authors:  Kavita Sharma; David A Kass
Journal:  Circ Res       Date:  2014-06-20       Impact factor: 17.367

4.  A potential linkage between mitochondrial function of the heart and leg muscles in patients with heart failure.

Authors:  Takao Kato; Eisaku Nakane; Moritoshi Funasako; Shoichi Miyamoto; Toshiaki Izumi; Tetsuya Haruna; Ryuji Nohara; Moriaki Inoko
Journal:  Int J Cardiol       Date:  2015-04-08       Impact factor: 4.164

5.  Determinants of exercise intolerance in elderly heart failure patients with preserved ejection fraction.

Authors:  Mark J Haykowsky; Peter H Brubaker; Jerry M John; Kathryn P Stewart; Timothy M Morgan; Dalane W Kitzman
Journal:  J Am Coll Cardiol       Date:  2011-07-12       Impact factor: 24.094

6.  Dietary nitrate supplementation reduces the O2 cost of low-intensity exercise and enhances tolerance to high-intensity exercise in humans.

Authors:  Stephen J Bailey; Paul Winyard; Anni Vanhatalo; Jamie R Blackwell; Fred J Dimenna; Daryl P Wilkerson; Joanna Tarr; Nigel Benjamin; Andrew M Jones
Journal:  J Appl Physiol (1985)       Date:  2009-08-06

7.  Impact of CARDIOrespiratory FITness on Arrhythmia Recurrence in Obese Individuals With Atrial Fibrillation: The CARDIO-FIT Study.

Authors:  Rajeev K Pathak; Adrian Elliott; Melissa E Middeldorp; Megan Meredith; Abhinav B Mehta; Rajiv Mahajan; Jeroen M L Hendriks; Darragh Twomey; Jonathan M Kalman; Walter P Abhayaratna; Dennis H Lau; Prashanthan Sanders
Journal:  J Am Coll Cardiol       Date:  2015-06-22       Impact factor: 24.094

8.  Effect of moderate diet-induced weight loss and weight regain on cardiovascular structure and function.

Authors:  Lisa de las Fuentes; Alan D Waggoner; B Selma Mohammed; Richard I Stein; Bernard V Miller; Gary D Foster; Holly R Wyatt; Samuel Klein; Victor G Davila-Roman
Journal:  J Am Coll Cardiol       Date:  2009-12-15       Impact factor: 24.094

9.  Differences in arterial compliance, microvascular function and venous capacitance between patients with heart failure and either preserved or reduced left ventricular systolic function.

Authors:  Sean Balmain; Neal Padmanabhan; William R Ferrell; John J Morton; John J V McMurray
Journal:  Eur J Heart Fail       Date:  2007-07-19       Impact factor: 15.534

Review 10.  Exercise intolerance in heart failure with preserved ejection fraction: more than a heart problem.

Authors:  Bharathi Upadhya; Mark J Haykowsky; Joel Eggebeen; Dalane W Kitzman
Journal:  J Geriatr Cardiol       Date:  2015-05       Impact factor: 3.327
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  12 in total

1.  Effect of High-Intensity Interval Training, Moderate Continuous Training, or Guideline-Based Physical Activity Advice on Peak Oxygen Consumption in Patients With Heart Failure With Preserved Ejection Fraction: A Randomized Clinical Trial.

Authors:  Stephan Mueller; Ephraim B Winzer; André Duvinage; Andreas B Gevaert; Frank Edelmann; Bernhard Haller; Elisabeth Pieske-Kraigher; Paul Beckers; Anna Bobenko; Jennifer Hommel; Caroline M Van de Heyning; Katrin Esefeld; Pia von Korn; Jeffrey W Christle; Mark J Haykowsky; Axel Linke; Ulrik Wisløff; Volker Adams; Burkert Pieske; Emeline M van Craenenbroeck; Martin Halle
Journal:  JAMA       Date:  2021-02-09       Impact factor: 56.272

Review 2.  Exercise intervention in hospitalized heart failure patients, with emphasis on congestion-related complications: a review.

Authors:  Jirka Cops; Sibren Haesen; Bart De Moor; Wilfried Mullens; Dominique Hansen
Journal:  Heart Fail Rev       Date:  2020-03       Impact factor: 4.214

Review 3.  Domain Management Approach to Heart Failure in the Geriatric Patient: Present and Future.

Authors:  Eiran Z Gorodeski; Parag Goyal; Scott L Hummel; Ashok Krishnaswami; Sarah J Goodlin; Linda L Hart; Daniel E Forman; Nanette K Wenger; James N Kirkpatrick; Karen P Alexander
Journal:  J Am Coll Cardiol       Date:  2018-05-01       Impact factor: 24.094

Review 4.  Impaired Exercise Tolerance in Heart Failure: Role of Skeletal Muscle Morphology and Function.

Authors:  Wesley J Tucker; Mark J Haykowsky; Yaewon Seo; Elisa Stehling; Daniel E Forman
Journal:  Curr Heart Fail Rep       Date:  2018-12

Review 5.  Beyond the myocardium? SGLT2 inhibitors target peripheral components of reduced oxygen flux in the diabetic patient with heart failure with preserved ejection fraction.

Authors:  Mouhamed Nashawi; Omar Sheikh; Ayman Battisha; Mahnoor Mir; Robert Chilton
Journal:  Heart Fail Rev       Date:  2022-01       Impact factor: 4.214

6.  Meta-analysis addressing the impact of cardiovascular-acting medication on peak oxygen uptake of patients with HFpEF.

Authors:  Aristi Boulmpou; Marieta P Theodorakopoulou; Maria-Eleni Alexandrou; Afroditi K Boutou; Christodoulos E Papadopoulos; Eva Pella; Pantelis Sarafidis; Vassilios Vassilikos
Journal:  Heart Fail Rev       Date:  2022-01-24       Impact factor: 4.214

Review 7.  Pathophysiology of Exercise Intolerance and Its Treatment With Exercise-Based Cardiac Rehabilitation in Heart Failure With Preserved Ejection Fraction.

Authors:  Wesley J Tucker; Siddhartha S Angadi; Mark J Haykowsky; Michael D Nelson; Satyam Sarma; Corey R Tomczak
Journal:  J Cardiopulm Rehabil Prev       Date:  2020-01       Impact factor: 3.646

Review 8.  Cellular and molecular pathobiology of heart failure with preserved ejection fraction.

Authors:  Sumita Mishra; David A Kass
Journal:  Nat Rev Cardiol       Date:  2021-01-11       Impact factor: 49.421

Review 9.  Influence of physical exercise on microRNAs in skeletal muscle regeneration, aging and diseases.

Authors:  Simona Ultimo; Giorgio Zauli; Alberto M Martelli; Marco Vitale; James A McCubrey; Silvano Capitani; Luca M Neri
Journal:  Oncotarget       Date:  2018-03-30

10.  Protein acetylation in skeletal muscle mitochondria is involved in impaired fatty acid oxidation and exercise intolerance in heart failure.

Authors:  Masaya Tsuda; Arata Fukushima; Junichi Matsumoto; Shingo Takada; Naoya Kakutani; Hideo Nambu; Katsuma Yamanashi; Takaaki Furihata; Takashi Yokota; Koichi Okita; Shintaro Kinugawa; Toshihisa Anzai
Journal:  J Cachexia Sarcopenia Muscle       Date:  2018-08-30       Impact factor: 12.910
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