Literature DB >> 28784893

A tip from the nose: rhinocerebral mucormycosis in a patient with alcoholic liver cirrhosis and cocaine abuse, an uncommon association.

David Avelar Rodriguez1, Gabriel Ochoa Virgen1, Roberto Carlos Miranda Ackerman1.   

Abstract

We present the case of a 28-year-old man with a long-standing history of cocaine abuse and Child-Pugh class C alcoholic liver cirrhosis who developed severe lower respiratory tract infection complicated with septic shock and multiple organ dysfunction. He was managed in the intensive care unit. On the eighth day after admission, he developed a nose discolouration, which was initially thought to be associated with high-dose vasopressors. Despite the reduction of vasopressors, the lesion progressed rapidly. It was later diagnosed as rhinocerebral mucormycosis. Amphotericin B was administered, but unfortunately the patient succumbed to the complications postinfection. The association between alcoholic liver cirrhosis and rhinocerebral mucormycosis should be known and prompt recognition warrants immediate treatment. © BMJ Publishing Group Ltd (unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

Entities:  

Keywords:  adult intensive care; alcoholic liver disease; cirrhosis; infectious diseases

Mesh:

Year:  2017        PMID: 28784893      PMCID: PMC5623276          DOI: 10.1136/bcr-2017-220730

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN: 1757-790X


  2 in total

1.  Invasive pulmonary mucormycosis and aspergillosis in a patient with decompensated hepatic cirrhosis.

Authors:  Jon G Persichino; Argun D Can; Tam T Van; Michele N Matthews; Scott G Filler
Journal:  Med Mycol Case Rep       Date:  2018-03-06

2.  Invasive rhinocerebral mucormycosis in a patient with liver cirrhosis leading to fatal massive stroke.

Authors:  Taher Sabobeh; Kamran Mushtaq; Ahmed Elsotouhy; Adham A Ammar; Sameera Rashid
Journal:  Med Mycol Case Rep       Date:  2018-09-21
  2 in total

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