Literature DB >> 28784260

Blocking Bcl-2 resolves IL-13-mediated mucous cell hyperplasia in a Bik-dependent manner.

Hitendra S Chand1, Yohannes A Mebratu1, Philip J Kuehl2, Yohannes Tesfaigzi3.   

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Year:  2017        PMID： 28784260      PMCID： PMC5675799          DOI： 10.1016/j.jaci.2017.05.038

Source DB:  PubMed          Journal:  J Allergy Clin Immunol        ISSN： 0091-6749            Impact factor:   10.793


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  9 in total

1.  Regional particle size dependent deposition of inhaled aerosols in rats and mice.

Authors:  Philip J Kuehl; Tamara L Anderson; Gabriel Candelaria; Benjamin Gershman; Ky Harlin; Jacob Y Hesterman; Thomas Holmes; John Hoppin; Christian Lackas; Jeffrey P Norenberg; Hongang Yu; Jacob D McDonald
Journal:  Inhal Toxicol       Date:  2011-12-07       Impact factor: 2.724

Review 2.  Roles of apoptosis in airway epithelia.

Authors:  Yohannes Tesfaigzi
Journal:  Am J Respir Cell Mol Biol       Date:  2006-01-26       Impact factor: 6.914

3.  Bcl-2 sustains increased mucous and epithelial cell numbers in metaplastic airway epithelium.

Authors:  J Foster Harris; Mark J Fischer; Jon R Hotchkiss; Brett P Monia; Scott H Randell; Jack R Harkema; Yohannes Tesfaigzi
Journal:  Am J Respir Crit Care Med       Date:  2004-12-23       Impact factor: 21.405

4.  ABT-263: a potent and orally bioavailable Bcl-2 family inhibitor.

Authors:  Christin Tse; Alexander R Shoemaker; Jessica Adickes; Mark G Anderson; Jun Chen; Sha Jin; Eric F Johnson; Kennan C Marsh; Michael J Mitten; Paul Nimmer; Lisa Roberts; Stephen K Tahir; Yu Xiao; Xiufen Yang; Haichao Zhang; Stephen Fesik; Saul H Rosenberg; Steven W Elmore
Journal:  Cancer Res       Date:  2008-05-01       Impact factor: 12.701

5.  ABT-199, a potent and selective BCL-2 inhibitor, achieves antitumor activity while sparing platelets.

Authors:  Andrew J Souers; Joel D Leverson; Erwin R Boghaert; Scott L Ackler; Nathaniel D Catron; Jun Chen; Brian D Dayton; Hong Ding; Sari H Enschede; Wayne J Fairbrother; David C S Huang; Sarah G Hymowitz; Sha Jin; Seong Lin Khaw; Peter J Kovar; Lloyd T Lam; Jackie Lee; Heather L Maecker; Kennan C Marsh; Kylie D Mason; Michael J Mitten; Paul M Nimmer; Anatol Oleksijew; Chang H Park; Cheol-Min Park; Darren C Phillips; Andrew W Roberts; Deepak Sampath; John F Seymour; Morey L Smith; Gerard M Sullivan; Stephen K Tahir; Chris Tse; Michael D Wendt; Yu Xiao; John C Xue; Haichao Zhang; Rod A Humerickhouse; Saul H Rosenberg; Steven W Elmore
Journal:  Nat Med       Date:  2013-01-06       Impact factor: 53.440

6.  Intracellular insulin-like growth factor-1 induces Bcl-2 expression in airway epithelial cells.

Authors:  Hitendra S Chand; Jennifer Foster Harris; Yohannes Mebratu; Yangde Chen; Paul S Wright; Scott H Randell; Yohannes Tesfaigzi
Journal:  J Immunol       Date:  2012-03-28       Impact factor: 5.422

Review 7.  Type 2 cytokines: mechanisms and therapeutic strategies.

Authors:  Thomas A Wynn
Journal:  Nat Rev Immunol       Date:  2015-04-17       Impact factor: 53.106

Review 8.  Thirty years of BCL-2: translating cell death discoveries into novel cancer therapies.

Authors:  Alex R D Delbridge; Stephanie Grabow; Andreas Strasser; David L Vaux
Journal:  Nat Rev Cancer       Date:  2016-02       Impact factor: 60.716

9.  A genetic variant of p53 restricts the mucous secretory phenotype by regulating SPDEF and Bcl-2 expression.

Authors:  Hitendra S Chand; Gilbert Montano; Xuesong Huang; Scott H Randell; Yohannes Mebratu; Hans Petersen; Yohannes Tesfaigzi
Journal:  Nat Commun       Date:  2014-11-27       Impact factor: 14.919
  9 in total
  7 in total

1.  Increased Expression of LASI lncRNA Regulates the Cigarette Smoke and COPD Associated Airway Inflammation and Mucous Cell Hyperplasia.

Authors:  Marko Manevski; Dinesh Devadoss; Christopher Long; Shashi P Singh; Mohd Wasim Nasser; Glen M Borchert; Madhavan N Nair; Irfan Rahman; Mohan Sopori; Hitendra S Chand
Journal:  Front Immunol       Date:  2022-06-14       Impact factor: 8.786

2.  IL-13 in LPS-Induced Inflammation Causes Bcl-2 Expression to Sustain Hyperplastic Mucous cells.

Authors:  Hitendra S Chand; Jennifer F Harris; Yohannes Tesfaigzi
Journal:  Sci Rep       Date:  2018-01-11       Impact factor: 4.379

3.  A Small Molecule BH3-mimetic Suppresses Cigarette Smoke-Induced Mucous Expression in Airway Epithelial Cells.

Authors:  Shah S Hussain; Shebin George; Shashi Singh; Rahul Jayant; Chien-An Hu; Mohan Sopori; Hitendra S Chand
Journal:  Sci Rep       Date:  2018-09-14       Impact factor: 4.379

4.  Acetylcholinesterase Inhibitor Pyridostigmine Bromide Attenuates Gut Pathology and Bacterial Dysbiosis in a Murine Model of Ulcerative Colitis.

Authors:  Shashi P Singh; Hitendra S Chand; Santanu Banerjee; Hemant Agarwal; Veena Raizada; Sabita Roy; Mohan Sopori
Journal:  Dig Dis Sci       Date:  2019-10-23       Impact factor: 3.199

5.  Effects of Wood Smoke Constituents on Mucin Gene Expression in Mice and Human Airway Epithelial Cells and on Nasal Epithelia of Subjects with a Susceptibility Gene Variant in Tp53.

Authors:  Dereje Tassew; Susan Fort; Yohannes Mebratu; Jacob McDonald; Hong Wei Chu; Hans Petersen; Yohannes Tesfaigzi
Journal:  Environ Health Perspect       Date:  2022-01-24       Impact factor: 9.031

6.  HIV-1 Productively Infects and Integrates in Bronchial Epithelial Cells.

Authors:  Dinesh Devadoss; Shashi P Singh; Arpan Acharya; Kieu Chinh Do; Palsamy Periyasamy; Marko Manevski; Neerad Mishra; Carmen S Tellez; Sundaram Ramakrishnan; Steven A Belinsky; Siddappa N Byrareddy; Shilpa Buch; Hitendra S Chand; Mohan Sopori
Journal:  Front Cell Infect Microbiol       Date:  2021-02-04       Impact factor: 5.293

7.  A long noncoding RNA antisense to ICAM-1 is involved in allergic asthma associated hyperreactive response of airway epithelial cells.

Authors:  Dinesh Devadoss; Grant Daly; Marko Manevski; Dominika Houserova; Shah S Hussain; Nathalie Baumlin; Matthias Salathe; Glen M Borchert; Raymond J Langley; Hitendra S Chand
Journal:  Mucosal Immunol       Date:  2020-10-29       Impact factor: 7.313
  7 in total

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