| Literature DB >> 28782963 |
Guanglong Sun1,2, Xue Lv1,2, Yinan Zhang3, Min Lei1,2, Lihong Hu3.
Abstract
A facile and practical method for the synthesis of aromatic aldehydes by palladium-catalyzed reductive carbonylation starting from aryl iodides and HCOOH is described. Compared to the known formylation procedure, HCOOH serves not only as the most convenient and environmental-friendly C1 source but also as the reviving agent in the reductive elimination process of a Pd-catalyst. Furthermore, this procedure is also applied successfully to the modification of natural products, such as vindoline, tabersonin, and vincamine, to obtain the corresponding products in good yields.Entities:
Year: 2017 PMID： 28782963 DOI： 10.1021/acs.orglett.7b01882
Source DB: PubMed Journal: Org Lett ISSN： 1523-7052 Impact factor: 6.005