Literature DB >> 28782475

The Therapeutical Effect of Chinese Medicine for the Treatment of Atherosclerotic Coronary Heart Disease.

Jian Zhang1, Hui Meng2, Yi Zhang2, Xuefeng Zhang1, MingYan Shao1, Chun Li2, Pengfei Tu2,3.   

Abstract

Coronary heart disease (CHD) is the leading cause of mortality in the world and atherosclerosis is the main cause of CHD. Traditional Chinese medicines have been applied in the treatment of CHD for centuries. In the recent years, clinical trials have been carried out to evaluate the efficacies of Chinese medicine. Meanwhile, extensive studies have also been carried out to explore the underlying pharmacological mechanisms of Chinese medicine. In this review, we will summarize the commonly prescribed Chinese medicine and patent Chinese drugs in treating patients with atherosclerotic CHD and review published clinical trials of Chinese medicine in treating CHD. The anti-atherosclerosis mechanism of Chinese medicine will also be reviewed. Finally, challenges and opportunities facing application of Chinese medicine in the treatment of CHD will be presented. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.org.

Entities:  

Keywords:  Atherosclerosis; Chinese medicine; Coronary heart disease; clinical trials; patent Chinese drugs; pharmacological mechanisms

Mesh:

Substances:

Year:  2017        PMID: 28782475     DOI: 10.2174/1381612823666170803101602

Source DB:  PubMed          Journal:  Curr Pharm Des        ISSN: 1381-6128            Impact factor:   3.116


  10 in total

1.  Quantitative and systems pharmacology 4. Network-based analysis of drug pleiotropy on coronary artery disease.

Authors:  Jiansong Fang; Chuipu Cai; Yanting Chai; Jingwei Zhou; Yujie Huang; Li Gao; Qi Wang; Feixiong Cheng
Journal:  Eur J Med Chem       Date:  2018-10-15       Impact factor: 6.514

2.  Exploring the mechanism of Shengmai Yin for coronary heart disease based on systematic pharmacology and chemoinformatics.

Authors:  Yan Jiang; Qi He; Tianqing Zhang; Wang Xiang; Zhiyong Long; Shiwei Wu
Journal:  Biosci Rep       Date:  2020-06-26       Impact factor: 3.840

3.  Adjuvant treatment of coronary heart disease angina pectoris with Chinese patent medicine: A prospective clinical cohort study.

Authors:  Yijia Liu; Zhu Li; Dandan Shen; Yanqi Song; Mengnan Huang; Xiaoxue Xue; Jing Xie; Ziyi Jiao; Shuming Gao; Yilan Xu; Shan Gao; Xianliang Wang; Qiang Xu; Sheng Gao; Chunjie Li; Lin Li; Kaijun Niu; Chunquan Yu
Journal:  Medicine (Baltimore)       Date:  2019-08       Impact factor: 1.889

4.  Pharmacological Network Reveals the Active Mechanism of Qi-Replenishing, Spleen-Strengthening, Phlegm-Dispelling, and Blood-Nourishing Fufang on Coronary Heart Disease.

Authors:  Fan Zhang; Yue Liu; Sicheng Zheng; Boyi Dang; Jianan Wang; Zhe Zhang
Journal:  Evid Based Complement Alternat Med       Date:  2020-12-29       Impact factor: 2.629

5.  Literature-Based Drug Repurposing in Traditional Chinese Medicine: Reduced Inflammatory M1 Macrophage Polarization by Jisil Haebaek Gyeji-Tang Alleviates Cardiovascular Disease In Vitro and Ex Vivo.

Authors:  Ga-Ram Yu; Seung-Jun Lee; Da-Hoon Kim; Dong-Woo Lim; Hyuck Kim; Won-Hwan Park; Jai-Eun Kim
Journal:  Evid Based Complement Alternat Med       Date:  2020-12-07       Impact factor: 2.629

6.  Systematic insight into the active constituents and mechanism of Guiqi Baizhu for the treatment of gastric cancer.

Authors:  Ling Li; Xiao-Jie Jin; Jia-Wei Li; Cheng-Hao Li; Shuang-Yan Zhou; Jun-Jie Li; Cai-Qin Feng; Dong-Ling Liu; Yong-Qi Liu
Journal:  Cancer Sci       Date:  2021-03-07       Impact factor: 6.716

7.  The Material Basis and Mechanism of Xuefu Zhuyu Decoction in Treating Stable Angina Pectoris and Unstable Angina Pectoris.

Authors:  Guanpeng Qi; Kaiwen Jiang; Jiaming Qu; Aijun Zhang; Ze Xu; Zhaohang Li; Xiaosong Zheng; Zuojing Li
Journal:  Evid Based Complement Alternat Med       Date:  2022-01-31       Impact factor: 2.629

8.  Prediction and validation of potential molecular targets for the combination of Astragalus membranaceus and Angelica sinensis in the treatment of atherosclerosis based on network pharmacology.

Authors:  Tianyue Wang; Yaqiong Zhou; Kaina Wang; Xinyu Jiang; Jingbo Wang; Jing Chen
Journal:  Medicine (Baltimore)       Date:  2022-07-01       Impact factor: 1.817

9.  Prediction of Molecular Mechanisms for LianXia NingXin Formula: A Network Pharmacology Study.

Authors:  Yang Yang; Kuo Yang; Teng Hao; Guodong Zhu; Ruby Ling; Xuezhong Zhou; Ping Li
Journal:  Front Physiol       Date:  2018-05-08       Impact factor: 4.566

10.  Shen-Hong-Tong-Luo Formula Attenuates Macrophage Inflammation and Lipid Accumulation through the Activation of the PPAR-γ/LXR-α/ABCA1 Pathway.

Authors:  Zepeng Zhang; Lu Zhai; Jing Lu; Sanmiao Sun; Dandan Wang; Daqing Zhao; Liwei Sun; Weimin Zhao; Xiangyan Li; Ying Chen
Journal:  Oxid Med Cell Longev       Date:  2020-10-01       Impact factor: 6.543

  10 in total

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