| Literature DB >> 28782421 |
Isaac Makundi1,2,3,4,5, Yushi Koshida1,2,3,4,5, Kyohei Kuse1,2,3,4,5, Takahiro Hiratsuka1,2,3,4,5, Jumpei Ito1,2,3,4,5, Takuya Baba1,2,3,4,5, Shinya Watanabe1,2,3,4,5, Maki Kawamura1,2,3,4,5, Yuka Odahara1,2,3,4,5, Ariko Miyake1,2,3,4,5, Hanae Yamamoto1,2,3,4,5, Sawako Kuniyoshi1,2,3,4,5, Manabu Onuma1,2,3,4,5, Kazuo Nishigaki1,2,3,4,5.
Abstract
The Tsushima leopard cat (TLC) Prionailurus bengalensis euptilurus, a subspecies of P. bengalensis, is designated a National Natural Monument of Japan, and lives only on Tsushima Island, Nagasaki Prefecture, Japan. TLCs are threatened by various infectious diseases. Feline leukemia virus (FeLV) causes a serious infectious disease with a poor prognosis in cats. Therefore, the transmission of FeLV from Tsushima domestic cats (TDCs) to TLCs may threaten the TLC population. We investigated the FeLV infection status of both TDCs and TLCs on Tsushima Island by screening blood samples for FeLV p27 antigen and using PCR to amplify the full-length FeLV env gene. The prevalence of FeLV was 6.4% in TDCs and 0% in TLCs. We also demonstrated that the virus can replicate in the cells of TLCs, suggesting its potential cross-species transmission. The viruses in TDCs were classified as genotype I/clade 3, which is prevalent on a nearby island, based on previous studies of FeLV genotypes and FeLV epidemiology. The FeLV viruses identified on Tsushima Island can be further divided into 2 lineages within genotype I/clade 3, which are geographically separated in Kamijima and Shimojima, indicating that FeLV may have been transmitted to Tsushima Island at least twice. Monitoring FeLV infection in the TDC and TLC populations is highly recommended as part of the TLC surveillance and management strategy.Entities:
Keywords: Epidemiology; feline leukemia virus; wildlife management
Mesh：
Year: 2017 PMID： 28782421 DOI： 10.1177/1040638717725551
Source DB: PubMed Journal: J Vet Diagn Invest ISSN： 1040-6387 Impact factor: 1.279