Literature DB >> 28782384

Skin microneedling plus platelet-rich plasma versus skin microneedling alone in the treatment of atrophic post acne scars: a split face comparative study.

Mohamed Kotb Ibrahim1, Shady Mahmoud Ibrahim1, Amany Mohamed Salem1.   

Abstract

INTRODUCTION: Acne scarring is a permanent disfiguring sequel, which can take varied morphological forms. Many therapeutic measures have been performed to improve acne scarring such as microneedling. Our objective is to evaluate the efficacy and safety of microneedling alone versus microneedling combined with platelet rich plasma in the treatment of post acne.
METHODS: The study included 35 patients with mild to severe post acne atrophic scar. All the patients received four sequential treatments of skin microneedling alone on the right side of the face and skin microneedling followed by topical application of platelet rich plasma (PRP) on the left side of the face with an interval of 3 weeks. Two blinded dermatologists evaluated the clinical response according to qualitative global acne scarring system grading of Goodman & Baron. Patients are queried about their satisfaction with the treatment outcomes.
RESULTS: The study included 35 patients with a mean age of 24.7 ± 6.8 years. There was a significant improvement in the degree of scar severity before and after treatment on both the sides. Regarding patient's satisfaction grades, there was a significant improvement after both treatment modalities with insignificant differences between both treatment modalities.
CONCLUSIONS: Both microneedling and microneedling in combined with PRP showed satisfactory results.

Entities:  

Keywords:  Microneedling; PRP; scar

Mesh:

Year:  2017        PMID: 28782384     DOI: 10.1080/09546634.2017.1365111

Source DB:  PubMed          Journal:  J Dermatolog Treat        ISSN: 0954-6634            Impact factor:   3.359


  14 in total

1.  An Assessment of Microneedling with Topical Growth Factors for Facial Skin Rejuvenation: A Randomized Controlled Trial.

Authors:  Miesha Merati; Christi Woods; Nina Reznik; Lydia Parker
Journal:  J Clin Aesthet Dermatol       Date:  2020-11-01

Review 2.  Platelet-rich Plasma, Collagen Peptides, and Stem Cells for Cutaneous Rejuvenation.

Authors:  Jordan V Wang; Elizabeth Schoenberg; Nazanin Saedi; Omer Ibrahim
Journal:  J Clin Aesthet Dermatol       Date:  2020-01-01

Review 3.  Platelet-Rich Plasma: A Comprehensive Review of Emerging Applications in Medical and Aesthetic Dermatology.

Authors:  Christopher White; Allyson Brahs; David Dorton; Kristin Witfill
Journal:  J Clin Aesthet Dermatol       Date:  2021-11

4.  A Randomized Study to Evaluate the Efficacy Fractional CO2Laser, Microneedling and Platelet Rich Plasma in Post-Acne Scarring.

Authors:  T Pooja; K V T Gopal; T Narayana Rao; B Gayatri Devi; S Ashwin Kumar
Journal:  Indian Dermatol Online J       Date:  2020-05-10

5.  Split-face Comparative Study of Efficacy of Platelet-rich Plasma Combined with Microneedling versus Microneedling alone in Treatment of Post-acne Scars.

Authors:  A S Nandini; Sana M Sankey; C S Sowmya; B C Sharath Kumar
Journal:  J Cutan Aesthet Surg       Date:  2021 Jan-Mar

6.  A Comparative Study of Microneedling Alone Versus Along with Platelet-Rich Plasma in Acne Scars.

Authors:  Meghna Gupta; Krishna Deb Barman; Rashmi Sarkar
Journal:  J Cutan Aesthet Surg       Date:  2021 Jan-Mar

Review 7.  The evidence behind the use of platelet-rich plasma (PRP) in scar management: a literature review.

Authors:  Osaid H Alser; Ioannis Goutos
Journal:  Scars Burn Heal       Date:  2018-11-18

Review 8.  Microneedling for the Treatment of Scars: An Update for Clinicians.

Authors:  Margit L W Juhasz; Joel L Cohen
Journal:  Clin Cosmet Investig Dermatol       Date:  2020-12-22

9.  Platelet-Rich Plasma in Aesthetics.

Authors:  Soni Nanda; Kavish Chauhan; Vinma Shetty; Shuken Dashore; Satish Bhatia
Journal:  Indian Dermatol Online J       Date:  2021-11-25

Review 10.  Platelet-Rich Plasma in Facial Rejuvenation: A Systematic Appraisal of the Available Clinical Evidence.

Authors:  Hong Xiao; Dan Xu; Rui Mao; Minqin Xiao; Yang Fang; Yin Liu
Journal:  Clin Cosmet Investig Dermatol       Date:  2021-11-16
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