Literature DB >> 28780660

Update on Valvular Heart Disease in Pregnancy.

Lucy M Safi1, Sarah V Tsiaras2.   

Abstract

OPINION STATEMENT: Valvular heart disease in women of childbearing age poses an increased risk of adverse maternal and fetal outcomes, and management in pregnancy can be challenging. Ideally, patients with suspected valvular disease should have preconception counseling by a multidisciplinary team including cardiologists with expertise in pregnancy and a maternal-fetal medicine specialist. Preconception planning should include a cardiac assessment of maternal risk, determination of frequency of surveillance, and a cardiovascular management plan during delivery. Women with valvular heart disease should be followed closely by a cardiologist and monitored for signs and symptoms of congestive heart failure and arrhythmias. In general, stenotic lesions may become more symptomatic in pregnancy, whereas regurgitant lesions are generally well tolerated. Left-sided valvular lesions have higher complication rates than right-sided lesions. For patients with asymptomatic valvular stenosis, medical management during pregnancy may include beta blockade and/or diuretics. Exercise stress testing prior to pregnancy in sedentary patients can be helpful to unmask symptoms and determine functional capacity. Patients with symptomatic, severe left-sided valvular obstruction have a high maternal risk of cardiovascular events during pregnancy, and percutaneous balloon valvuloplasty or surgery is recommended prior to pregnancy. The type of prosthetic valve (mechanical vs bioprosthetic) should be selected after a careful discussion with the patient. Invasive procedures are generally reserved for when medical management fails. The second trimester may be the optimal time for intervention as fetal organogenesis is complete and the cardiac positioning has not been affected by the gravid uterus.

Entities:  

Keywords:  Pregnancy; Valve disease in pregnancy; Valvular heart disease

Year:  2017        PMID: 28780660     DOI: 10.1007/s11936-017-0570-2

Source DB:  PubMed          Journal:  Curr Treat Options Cardiovasc Med        ISSN: 1092-8464


  27 in total

1.  Prospective multicenter study of pregnancy outcomes in women with heart disease.

Authors:  S C Siu; M Sermer; J M Colman; A N Alvarez; L A Mercier; B C Morton; C M Kells; M L Bergin; M C Kiess; F Marcotte; D A Taylor; E P Gordon; J C Spears; J W Tam; K S Amankwah; J F Smallhorn; D Farine; S Sorensen
Journal:  Circulation       Date:  2001-07-31       Impact factor: 29.690

Review 2.  Management of Pregnancy in Patients With Complex Congenital Heart Disease: A Scientific Statement for Healthcare Professionals From the American Heart Association.

Authors:  Mary M Canobbio; Carole A Warnes; Jamil Aboulhosn; Heidi M Connolly; Amber Khanna; Brian J Koos; Seema Mital; Carl Rose; Candice Silversides; Karen Stout
Journal:  Circulation       Date:  2017-01-12       Impact factor: 29.690

Review 3.  Mitral valve prolapse in pregnancy.

Authors:  T Cowles; B Gonik
Journal:  Semin Perinatol       Date:  1990-02       Impact factor: 3.300

4.  Pregnancy in Women With a Mechanical Heart Valve: Data of the European Society of Cardiology Registry of Pregnancy and Cardiac Disease (ROPAC).

Authors:  Iris M van Hagen; Jolien W Roos-Hesselink; Titia P E Ruys; Waltraut M Merz; Sorel Goland; Harald Gabriel; Malgorzata Lelonek; Olga Trojnarska; Wael Abdulrahman Al Mahmeed; Hajnalka Olga Balint; Zeinab Ashour; Helmut Baumgartner; Eric Boersma; Mark R Johnson; Roger Hall
Journal:  Circulation       Date:  2015-06-22       Impact factor: 29.690

5.  Dose-dependent fetal complications of warfarin in pregnant women with mechanical heart valves.

Authors:  N Vitale; M De Feo; L S De Santo; A Pollice; N Tedesco; M Cotrufo
Journal:  J Am Coll Cardiol       Date:  1999-05       Impact factor: 24.094

6.  ESC Guidelines on the management of cardiovascular diseases during pregnancy: the Task Force on the Management of Cardiovascular Diseases during Pregnancy of the European Society of Cardiology (ESC).

Authors:  Vera Regitz-Zagrosek; Carina Blomstrom Lundqvist; Claudio Borghi; Renata Cifkova; Rafael Ferreira; Jean-Michel Foidart; J Simon R Gibbs; Christa Gohlke-Baerwolf; Bulent Gorenek; Bernard Iung; Mike Kirby; Angela H E M Maas; Joao Morais; Petros Nihoyannopoulos; Petronella G Pieper; Patrizia Presbitero; Jolien W Roos-Hesselink; Maria Schaufelberger; Ute Seeland; Lucia Torracca
Journal:  Eur Heart J       Date:  2011-08-26       Impact factor: 29.983

7.  Anticoagulation in pregnant women with mechanical heart valve prostheses.

Authors:  S S Meschengieser; C G Fondevila; M T Santarelli; M A Lazzari
Journal:  Heart       Date:  1999-07       Impact factor: 5.994

8.  Vascular matrix remodeling in patients with bicuspid aortic valve malformations: implications for aortic dilatation.

Authors:  Paul W M Fedak; Mauro P L de Sa; Subodh Verma; Nafiseh Nili; Pedram Kazemian; Jagdish Butany; Bradley H Strauss; Richard D Weisel; Tirone E David
Journal:  J Thorac Cardiovasc Surg       Date:  2003-09       Impact factor: 5.209

9.  Thrombolytic therapy for the treatment of prosthetic heart valve thrombosis in pregnancy with low-dose, slow infusion of tissue-type plasminogen activator.

Authors:  Mehmet Özkan; Beytullah Çakal; Süleyman Karakoyun; Ozan Mustafa Gürsoy; Cihan Çevik; Macit Kalçık; Ali Emrah Oğuz; Sabahattin Gündüz; Mehmet Ali Astarcioglu; Ahmet Çağrı Aykan; Zübeyde Bayram; Murat Biteker; Evren Kaynak; Gökhan Kahveci; Nilüfer Ekşi Duran; Mustafa Yıldız
Journal:  Circulation       Date:  2013-06-28       Impact factor: 29.690

Review 10.  Anticoagulation for pregnant women with mechanical heart valves: a systematic review and meta-analysis.

Authors:  Rohan D'Souza; Jackie Ostro; Prakesh S Shah; Candice K Silversides; Ann Malinowski; Kellie E Murphy; Mathew Sermer; Nadine Shehata
Journal:  Eur Heart J       Date:  2017-05-14       Impact factor: 29.983

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  4 in total

Review 1.  Sex Differences and Similarities in Valvular Heart Disease.

Authors:  Jacqueline T DesJardin; Joanna Chikwe; Rebecca T Hahn; Judy W Hung; Francesca N Delling
Journal:  Circ Res       Date:  2022-02-17       Impact factor: 17.367

Review 2.  The Use of Echocardiography and Advanced Cardiac Ultrasonography During Pregnancy.

Authors:  Anna C O'Kelly; Garima Sharma; Arthur Jason Vaught; Sammy Zakaria
Journal:  Curr Treat Options Cardiovasc Med       Date:  2019-11-21

3.  Reducing Disparities in Severe Maternal Morbidity and Mortality.

Authors:  Elizabeth A Howell
Journal:  Clin Obstet Gynecol       Date:  2018-06       Impact factor: 2.190

Review 4.  Echocardiography for the Pregnant Heart.

Authors:  Henrietta A Afari; Esther F Davis; Amy A Sarma
Journal:  Curr Treat Options Cardiovasc Med       Date:  2021-05-28
  4 in total

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