Literature DB >> 2877965

Influence of triamcinolone and somatostatin on morphometric parameters of cultured intestinal mucosa.

A Schneider, G Grösch, E F Stange, H Ditschuneit.   

Abstract

Mucosal biopsies from rabbit ileum were organ cultured for 24 h. The influence of triamcinolone and somatostatin on villus height and diameter as well as crypt depth and the number of mitoses was measured at various times during 24 h of culture as indices of cell proliferation and tissue maintenance. It could be shown that triamcinolone reduced cell proliferation slightly but preserved mucosal structure in organ culture. Somatostatin inhibited crypt cell proliferation, without any effect on other morphological parameters.

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Year:  1986        PMID: 2877965     DOI: 10.1007/bf02623478

Source DB:  PubMed          Journal:  In Vitro Cell Dev Biol        ISSN: 0883-8364


  39 in total

1.  Corticosteroids and growth.

Authors:  J N Loeb
Journal:  N Engl J Med       Date:  1976-09-02       Impact factor: 91.245

2.  Inhibitory effects of somatostatin on growth and differentiation in cultured intestinal mucosa.

Authors:  E F Stange; A Schneider; V Schusdziarra; H Ditschuneit
Journal:  Horm Metab Res       Date:  1984-02       Impact factor: 2.936

3.  Glucocorticoids and intestinal cell proliferation.

Authors:  J Scott; R M Batt; T J Peters
Journal:  N Engl J Med       Date:  1978-10-19       Impact factor: 91.245

4.  Control of brush border enzymes by dexamethasone in the fetal rat intestine cultured in vitro.

Authors:  P M Simon-Assmann; M Kedinger; J F Grenier; K Haffen
Journal:  J Pediatr Gastroenterol Nutr       Date:  1982       Impact factor: 2.839

Review 5.  Organ culture of gastric mucosa: advantages and limitations.

Authors:  R M Donaldson; C R Kapadia
Journal:  Methods Cell Biol       Date:  1980       Impact factor: 1.441

6.  Morphological development of the epithelium of the embryonic chick intestine in culture: influence of thyroxine and hydrocortisone.

Authors:  B L Black
Journal:  Am J Anat       Date:  1978-12

7.  Organ culture of the mucosa of human small intestine.

Authors:  J S Trier
Journal:  Methods Cell Biol       Date:  1980       Impact factor: 1.441

8.  [Quantitative investigations of the structure and function of the intestinal mucosa in endoscopically obtained biopsy material. Findings in patients with coeliac disease, patients with partially resected small intestine in Crohn's disease and in patients with small intestine resection for other reasons (author's transl)].

Authors:  H Lorenz-Meyer; K Ziegler; M Böger; G Adler; H Rohde; W Brandes
Journal:  Z Gastroenterol       Date:  1980-12       Impact factor: 2.000

9.  Lipoprotein synthesis and secretion by cultured human intestinal mucosa.

Authors:  D Rachmilewitz; P Sharon; S Eisenberg
Journal:  Eur J Clin Invest       Date:  1980-04       Impact factor: 4.686

10.  Effect of somatostatin on normal and gastric-stimulated cell proliferation in the gastric and intestinal mucosae of the rat.

Authors:  T Lehy; M Dubrasquet; S Bonfils
Journal:  Digestion       Date:  1979       Impact factor: 3.216

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  1 in total

1.  Sandostatin impairs postresection intestinal adaptation in a rat model of short bowel syndrome.

Authors:  Igor Sukhotnik; Kamal Khateeb; Michael M Krausz; Edmund Sabo; Leonardo Siplovich; Arnold G Coran; Eitan Shiloni
Journal:  Dig Dis Sci       Date:  2002-09       Impact factor: 3.199

  1 in total

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