Literature DB >> 2877928

Adrenergic control of lipolysis and metabolic responses in obesity.

B Zahorska-Markiewicz, C Kucio, D Piskorska.   

Abstract

Adrenergic modulation of lipolysis was determined in obese and lean women. Epinephrine was infused alone, or in combination with propranolol, or with phentolamine. In both obese and lean subjects slight alpha- and prevalent beta-adrenergic lipolytic responsiveness was observed. alpha-adrenergic blockade by yohimbine potentiated lipolysis and exercise energy expenditure. Yohimbine application during the slimming treatment increased weight loss without side effects.

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Year:  1986        PMID: 2877928     DOI: 10.1055/s-2007-1012409

Source DB:  PubMed          Journal:  Horm Metab Res        ISSN: 0018-5043            Impact factor:   2.936


  4 in total

1.  Pharmacodynamic effects of chronic yohimbine treatment in healthy volunteers.

Authors:  J Galitzky; D Rivière; M A Tran; J L Montastruc; M Berlan
Journal:  Eur J Clin Pharmacol       Date:  1990       Impact factor: 2.953

2.  Lipomobilizing effects of procaterol and yohimbine in the conscious dog: comparison of endocrinological, metabolic and cardiovascular effects.

Authors:  P Valet; M Taouis; M A Tran; P Montastruc; M Lafontan; M Berlan
Journal:  Br J Pharmacol       Date:  1989-05       Impact factor: 8.739

3.  Thermogenic and lipolytic effect of yohimbine in the dog.

Authors:  J Galitzky; M Vermorel; M Lafontan; P Montastruc; M Berlan
Journal:  Br J Pharmacol       Date:  1991-10       Impact factor: 8.739

4.  Effects of physiological and pharmacological variation of sympathetic nervous system activity on plasma non-esterified fatty acid concentrations in man.

Authors:  P Barbe; J Galitzky; D Riviere; J M Senard; M Lafontan; M Garrigues; M Berlan
Journal:  Br J Clin Pharmacol       Date:  1993-07       Impact factor: 4.335

  4 in total

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