Literature DB >> 28777943

Mesenchymal Stem Cells in Fibrotic Disease.

Elie El Agha1, Rafael Kramann2, Rebekka K Schneider3, Xiaokun Li4, Werner Seeger5, Benjamin D Humphreys6, Saverio Bellusci7.   

Abstract

Fibrosis is associated with organ failure and high mortality and is commonly characterized by aberrant myofibroblast accumulation. Investigating the cellular origin of myofibroblasts in various diseases is thus a promising strategy for developing targeted anti-fibrotic treatments. Recent studies using genetic lineage tracing technology have implicated diverse organ-resident perivascular mesenchymal stem cell (MSC)-like cells and bone marrow-MSCs in myofibroblast generation during fibrosis development. In this Review, we give an overview of the emerging role of MSCs and MSC-like cells in myofibroblast-mediated fibrotic disease in the kidney, lung, heart, liver, skin, and bone marrow.
Copyright © 2017 Elsevier Inc. All rights reserved.

Entities:  

Keywords:  lineage tracing; mesenchymal stem cells; organ fibrosis

Mesh：

Year:  2017        PMID： 28777943     DOI： 10.1016/j.stem.2017.07.011

Source DB:  PubMed          Journal:  Cell Stem Cell        ISSN： 1875-9777            Impact factor:   24.633


  122 in total

1.  Myofibroblast Markers and Microscopy Detection Methods in Cell Culture and Histology.

Authors:  Fereshteh S Younesi; Dong Ok Son; Joao Firmino; Boris Hinz
Journal:  Methods Mol Biol       Date:  2021

2.  Mesenchymal Stem Cell/Red Blood Cell-Inspired Nanoparticle Therapy in Mice with Carbon Tetrachloride-Induced Acute Liver Failure.

Authors:  Hongxia Liang; Ke Huang; Teng Su; Zhenhua Li; Shiqi Hu; Phuong-Uyen Dinh; Emily A Wrona; Chen Shao; Li Qiao; Adam C Vandergriff; M Taylor Hensley; Jhon Cores; Tyler Allen; Hongyu Zhang; Qinglei Zeng; Jiyuan Xing; Donald O Freytes; Deliang Shen; Zujiang Yu; Ke Cheng
Journal:  ACS Nano       Date:  2018-06-26       Impact factor: 15.881

3.  Immunohistochemical study of renal fibropoiesis associated with dogs naturally and experimentally infected with two different strains of Leishmania (L.) infantum.

Authors:  Adriano F Alves; Ramon A Pereira; Helida M de Andrade; David M Mosser; Wagner L Tafuri
Journal:  Int J Exp Pathol       Date:  2019-11-06       Impact factor: 1.925

Review 4.  Resolution of organ fibrosis.

Authors:  Joon-Il Jun; Lester F Lau
Journal:  J Clin Invest       Date:  2018-01-02       Impact factor: 14.808

Review 5.  Mechanisms supporting potential use of bone marrow-derived mesenchymal stem cells in psychocardiology.

Authors:  Jianyang Liu; Lijun Zhang; Meiyan Liu
Journal:  Am J Transl Res       Date:  2019-11-15       Impact factor: 4.060

Review 6.  Inflammatory bone marrow microenvironment.

Authors:  Nils B Leimkühler; Rebekka K Schneider
Journal:  Hematology Am Soc Hematol Educ Program       Date:  2019-12-06

Review 7.  Lung-resident mesenchymal stromal cells are tissue-specific regulators of lung homeostasis.

Authors:  Stefanie Noel Sveiven; Tara M Nordgren
Journal:  Am J Physiol Lung Cell Mol Physiol       Date:  2020-05-13       Impact factor: 5.464

Review 8.  Mesenchymal stem cells: From regeneration to cancer.

Authors:  Peishan Li; Zheng Gong; Leonard D Shultz; Guangwen Ren
Journal:  Pharmacol Ther       Date:  2019-04-16       Impact factor: 12.310

9.  Parabiosis and single-cell RNA sequencing reveal a limited contribution of monocytes to myofibroblasts in kidney fibrosis.

Authors:  Rafael Kramann; Flavia Machado; Haojia Wu; Tetsuro Kusaba; Konrad Hoeft; Rebekka K Schneider; Benjamin D Humphreys
Journal:  JCI Insight       Date:  2018-05-03

10.  Induction of Fibrogenic Phenotype in Human Mesenchymal Stem Cells by Connective Tissue Growth Factor in a Hydrogel Model of Soft Connective Tissue.

Authors:  Aidan B Zerdoum; Eric W Fowler; Xinqiao Jia
Journal:  ACS Biomater Sci Eng       Date:  2019-07-30
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