Literature DB >> 2877711

Effects of divalent metal ions on the uptake of glutamate and GABA from synaptosomal fractions.

B Gabrielsson, T Robson, D Norris, S H Chung.   

Abstract

The effects of divalent metal ions on high affinity uptake glutamate and GABA were examined, using crude and purified synaptosomal fractions prepared from brains of DBA/2CBI. The uptake velocities of both amino acids are severely reduced in the presence of Cu2+, Fe2+ and Zn2+ but remain unaffected by Co2+.

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Year:  1986        PMID： 2877711     DOI： 10.1016/0006-8993(86)91157-1

Source DB:  PubMed          Journal:  Brain Res        ISSN： 0006-8993            Impact factor:   3.252


  8 in total

1.  Aging is associated with a decrease in synaptosomal glutamate uptake and an increase in the susceptibility of synaptosomal vitamin E to oxidative stress.

Authors:  G T Vatassery; J C Lai; W E Smith; H T Quach
Journal:  Neurochem Res       Date:  1998-02       Impact factor: 3.996

Review 2.  Copper-dependent functions for the prion protein.

Authors:  David R Brown; Judyth Sassoon
Journal:  Mol Biotechnol       Date:  2002-10       Impact factor: 2.695

3.  Cu(II) and Zn(II) ions alter the dynamics and distribution of Mn(II) in cultured chick glial cells.

Authors:  F C Wedler; B W Ley
Journal:  Neurochem Res       Date:  1990-12       Impact factor: 3.996

4.  Modulation by zinc of the glutamate transporters in glial cells and cones isolated from the tiger salamander retina.

Authors:  M Spiridon; D Kamm; B Billups; P Mobbs; D Attwell
Journal:  J Physiol       Date:  1998-01-15       Impact factor: 5.182

Review 5.  A potential role for alterations of zinc and zinc transport proteins in the progression of Alzheimer's disease.

Authors:  Mark A Lovell
Journal:  J Alzheimers Dis       Date:  2009       Impact factor: 4.472

6.  Zinc inhibits astrocyte glutamate uptake by activation of poly(ADP-ribose) polymerase-1.

Authors:  Sang Won Suh; Koji Aoyama; Conrad C Alano; Christopher M Anderson; Aaron M Hamby; Raymond A Swanson
Journal:  Mol Med       Date:  2007 Jul-Aug       Impact factor: 6.354

Review 7.  Iron and learning potential in childhood.

Authors:  B Lozoff
Journal:  Bull N Y Acad Med       Date:  1989-12

8.  Dietary zinc deficiency has no effect on auditory brainstem responses in the rat.

Authors:  J Wensink; H Hoeve; I Mertens zur Borg; C J Van den Hamer
Journal:  Biol Trace Elem Res       Date:  1989-10       Impact factor: 3.738
  8 in total

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