Literature DB >> 28777042

Unexpected metabolic function of a tRNA synthetase.

Abul Arif1, Paul L Fox1.   

Abstract

Keywords:  EPRS; FATP1; GAIT; S6K1; adiposity; insulin; interferon-gamma; mTORC1; metabolism; tRNA synthetase

Mesh：

Substances：

Year:  2017        PMID： 28777042      PMCID： PMC5788480          DOI： 10.1080/15384101.2017.1324127

Source DB:  PubMed          Journal:  Cell Cycle        ISSN： 1551-4005            Impact factor:   4.534


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  7 in total

Review 1.  Does protein phosphorylation play a role in translational control by eukaryotic aminoacyl-tRNA synthetases?

Authors:  M J Clemens
Journal:  Trends Biochem Sci       Date:  1990-05       Impact factor: 13.807

2.  Leucyl-tRNA synthetase is an intracellular leucine sensor for the mTORC1-signaling pathway.

Authors:  Jung Min Han; Seung Jae Jeong; Min Chul Park; Gyuyoup Kim; Nam Hoon Kwon; Hoi Kyoung Kim; Sang Hoon Ha; Sung Ho Ryu; Sunghoon Kim
Journal:  Cell       Date:  2012-03-15       Impact factor: 41.582

3.  Infection-specific phosphorylation of glutamyl-prolyl tRNA synthetase induces antiviral immunity.

Authors:  Eun-Young Lee; Hyun-Cheol Lee; Hyun-Kwan Kim; Song Yee Jang; Seong-Jun Park; Yong-Hoon Kim; Jong Hwan Kim; Jungwon Hwang; Jae-Hoon Kim; Tae-Hwan Kim; Abul Arif; Seon-Young Kim; Young-Ki Choi; Cheolju Lee; Chul-Ho Lee; Jae U Jung; Paul L Fox; Sunghoon Kim; Jong-Soo Lee; Myung Hee Kim
Journal:  Nat Immunol       Date:  2016-09-05       Impact factor: 25.606

4.  Two-site phosphorylation of EPRS coordinates multimodal regulation of noncanonical translational control activity.

Authors:  Abul Arif; Jie Jia; Rupak Mukhopadhyay; Belinda Willard; Michael Kinter; Paul L Fox
Journal:  Mol Cell       Date:  2009-07-31       Impact factor: 17.970

5.  Absence of S6K1 protects against age- and diet-induced obesity while enhancing insulin sensitivity.

Authors:  Sung Hee Um; Francesca Frigerio; Mitsuhiro Watanabe; Frédéric Picard; Manel Joaquin; Melanie Sticker; Stefano Fumagalli; Peter R Allegrini; Sara C Kozma; Johan Auwerx; George Thomas
Journal:  Nature       Date:  2004-08-11       Impact factor: 49.962

6.  EPRS is a critical mTORC1-S6K1 effector that influences adiposity in mice.

Authors:  Abul Arif; Fulvia Terenzi; Alka A Potdar; Jie Jia; Jessica Sacks; Arnab China; Dalia Halawani; Kommireddy Vasu; Xiaoxia Li; J Mark Brown; Jie Chen; Sara C Kozma; George Thomas; Paul L Fox
Journal:  Nature       Date:  2017-02-08       Impact factor: 49.962

7.  Ribosomal protein S6 kinase 1 signaling regulates mammalian life span.

Authors:  Colin Selman; Jennifer M A Tullet; Daniela Wieser; Elaine Irvine; Steven J Lingard; Agharul I Choudhury; Marc Claret; Hind Al-Qassab; Danielle Carmignac; Faruk Ramadani; Angela Woods; Iain C A Robinson; Eugene Schuster; Rachel L Batterham; Sara C Kozma; George Thomas; David Carling; Klaus Okkenhaug; Janet M Thornton; Linda Partridge; David Gems; Dominic J Withers
Journal:  Science       Date:  2009-10-02       Impact factor: 47.728
  7 in total
  1 in total

1.  KAE1 Allelic Variants Affect TORC1 Activation and Fermentation Kinetics in Saccharomyces cerevisiae.

Authors:  Eduardo I Kessi-Pérez; Francisco Salinas; Asier González; Ying Su; José M Guillamón; Michael N Hall; Luis F Larrondo; Claudio Martínez
Journal:  Front Microbiol       Date:  2019-07-31       Impact factor: 5.640
  1 in total

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