| Literature DB >> 2877666 |
J L Vayssiere, J C Larcher, F Berthelot, C Benlot, F Gros, B Croizat.
Abstract
CCA, a potent neuroblastoma differentiation inducer, was shown by oxygraphic measurements to reduce significantly the O2 consumption of whole neuroblastoma cells as of mitochondria purified from neuroblastoma or mouse cortex. The effect of CCA on the respiration was compared to those of oligomycin. Our results suggest that the molecular target of CCA is the matrix F1 catalytic component of the F0F1 mitochondrial ATPase.Entities:
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Year: 1986 PMID： 2877666 DOI： 10.1016/0006-291x(86)90703-5
Source DB: PubMed Journal: Biochem Biophys Res Commun ISSN： 0006-291X Impact factor: 3.575