Literature DB >> 28774814

The role of the serotonergic system in motor control.

Takashi Kawashima1.   

Abstract

The serotonergic system in the vertebrate brain is implicated in various behaviors and diseases. Its involvement in motor control has been studied for over half a century, but efforts to build a unified model of its functions have been hampered due to the complexity of serotonergic neuromodulation. This review summarizes the anatomical structure of the serotonergic system, its afferent and efferent connections to other brain regions, and recent insights into the sensorimotor computations in the serotonergic system, and considers future research directions into the roles of serotonergic system in motor control.
Copyright © 2017 Elsevier Ireland Ltd and Japan Neuroscience Society. All rights reserved.

Keywords:  Basal ganglia; Cerebellum; Motor control; Raphe nucleus; Serotonergic system; Serotonin; Spinal cord

Mesh:

Substances:

Year:  2017        PMID: 28774814     DOI: 10.1016/j.neures.2017.07.005

Source DB:  PubMed          Journal:  Neurosci Res        ISSN: 0168-0102            Impact factor:   3.304


  14 in total

1.  Morphological and electrophysiological properties of serotonin neurons with NMDA modulation in the mesencephalic locomotor region of neonatal ePet-EYFP mice.

Authors:  Renkai Ge; Ke Chen; Yi Cheng; Yue Dai
Journal:  Exp Brain Res       Date:  2019-11-12       Impact factor: 1.972

2.  Enhanced availability of serotonin increases activation of unfatigued muscle but exacerbates central fatigue during prolonged sustained contractions.

Authors:  Justin J Kavanagh; Amelia J McFarland; Janet L Taylor
Journal:  J Physiol       Date:  2018-11-08       Impact factor: 5.182

3.  Potassium Channel Conductance Is Involved in Phenylephrine-Induced Spontaneous Firing of Serotonergic Neurons in the Dorsal Raphe Nucleus.

Authors:  Jing Wang; Yingzi Wang; Xiaona Du; Hailin Zhang
Journal:  Front Cell Neurosci       Date:  2022-06-06       Impact factor: 6.147

4.  Perioperative Considerations for Patients With Major Depressive Disorder Undergoing Surgery.

Authors:  Edwin N Aroke; Alexis N Robinson; Bryan A Wilbanks
Journal:  J Perianesth Nurs       Date:  2020-01-16       Impact factor: 1.084

5.  Long-Term Effects of Intrauterine Exposure to Antidepressants on Physical, Neurodevelopmental, and Psychiatric Outcomes: A Systematic Review.

Authors:  Anna-Sophie Rommel; Veerle Bergink; Xiaoqin Liu; Trine Munk-Olsen; Nina Maren Molenaar
Journal:  J Clin Psychiatry       Date:  2020-05-12       Impact factor: 4.384

6.  A multi-omic study for uncovering molecular mechanisms associated with hyperammonemia-induced cerebellar function impairment in rats.

Authors:  Sonia Tarazona; Héctor Carmona; Ana Conesa; Marta Llansola; Vicente Felipo
Journal:  Cell Biol Toxicol       Date:  2021-01-06       Impact factor: 6.691

7.  Mapping the physiological and molecular markers of stress and SSRI antidepressant treatment in S100a10 corticostriatal neurons.

Authors:  Derya Sargin; Revathy U Chottekalapanda; Kristina E Perit; Victoria Yao; Duong Chu; Daniel W Sparks; Salina Kalik; Saige K Power; Olga G Troyanskaya; Eric F Schmidt; Paul Greengard; Evelyn K Lambe
Journal:  Mol Psychiatry       Date:  2019-08-20       Impact factor: 15.992

8.  Betahistine alleviates benign paroxysmal positional vertigo (BPPV) through inducing production of multiple CTRP family members and activating the ERK1/2-AKT/PPARy pathway.

Authors:  Jing Hui; Qi Lei; Zhi Ji; Dingjing Zi
Journal:  Biol Res       Date:  2022-04-04       Impact factor: 5.612

Review 9.  Silence, Solitude, and Serotonin: Neural Mechanisms Linking Hearing Loss and Social Isolation.

Authors:  Sarah M Keesom; Laura M Hurley
Journal:  Brain Sci       Date:  2020-06-12

10.  Three-Week Treadmill Exercise Enhances Persistent Inward Currents, Facilitates Dendritic Plasticity, and Upregulates the Excitability of Dorsal Raphe Serotonin Neurons in ePet-EYFP Mice.

Authors:  Renkai Ge; Yue Dai
Journal:  Front Cell Neurosci       Date:  2020-10-16       Impact factor: 5.505

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