| Literature DB >> 28774814 |
Abstract
The serotonergic system in the vertebrate brain is implicated in various behaviors and diseases. Its involvement in motor control has been studied for over half a century, but efforts to build a unified model of its functions have been hampered due to the complexity of serotonergic neuromodulation. This review summarizes the anatomical structure of the serotonergic system, its afferent and efferent connections to other brain regions, and recent insights into the sensorimotor computations in the serotonergic system, and considers future research directions into the roles of serotonergic system in motor control.Keywords: Basal ganglia; Cerebellum; Motor control; Raphe nucleus; Serotonergic system; Serotonin; Spinal cord
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Year: 2017 PMID: 28774814 DOI: 10.1016/j.neures.2017.07.005
Source DB: PubMed Journal: Neurosci Res ISSN: 0168-0102 Impact factor: 3.304