| Literature DB >> 28770842 |
Constanze Hoffmann1, Fee Zimmermann1,2, Roman Biek3, Hjalmar Kuehl4, Kathrin Nowak1, Roger Mundry4, Anthony Agbor4, Samuel Angedakin4, Mimi Arandjelovic4, Anja Blankenburg1, Gregory Brazolla4, Katherine Corogenes4, Emmanuel Couacy-Hymann5, Tobias Deschner4, Paula Dieguez4, Karsten Dierks4, Ariane Düx1, Susann Dupke2, Henk Eshuis4, Pierre Formenty6, Yisa Ginath Yuh4, Annemarie Goedmakers7, Jan F Gogarten1,4,8, Anne-Céline Granjon4, Scott McGraw9, Roland Grunow2, John Hart10, Sorrel Jones4, Jessica Junker4, John Kiang11, Kevin Langergraber12, Juan Lapuente4, Kevin Lee4, Siv Aina Leendertz1, Floraine Léguillon1, Vera Leinert13, Therese Löhrich1,4, Sergio Marrocoli4, Kerstin Mätz-Rensing14, Amelia Meier4, Kevin Merkel1, Sonja Metzger1, Mizuki Murai4, Svenja Niedorf1, Hélène De Nys1,4, Andreas Sachse1, Joost van Schijndel4, Ulla Thiesen1, Els Ton7, Doris Wu1,4, Lothar H Wieler15, Christophe Boesch4, Silke R Klee2, Roman M Wittig4, Sébastien Calvignac-Spencer1, Fabian H Leendertz1.
Abstract
Anthrax is a globally important animal disease and zoonosis. Despite this, our current knowledge of anthrax ecology is largely limited to arid ecosystems, where outbreaks are most commonly reported. Here we show that the dynamics of an anthrax-causing agent, Bacillus cereus biovar anthracis, in a tropical rainforest have severe consequences for local wildlife communities. Using data and samples collected over three decades, we show that rainforest anthrax is a persistent and widespread cause of death for a broad range of mammalian hosts. We predict that this pathogen will accelerate the decline and possibly result in the extirpation of local chimpanzee (Pan troglodytes verus) populations. We present the epidemiology of a cryptic pathogen and show that its presence has important implications for conservation.Entities:
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Year: 2017 PMID： 28770842 DOI： 10.1038/nature23309
Source DB: PubMed Journal: Nature ISSN： 0028-0836 Impact factor: 49.962