Nan Jiang1,2, Cheng-He Qin1, Yi-Long Hou2, Zi-Long Yao2, Bin Yu1,2. 1. Department of Orthopedics & Traumatology, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, PR China. 2. Guangdong Provincial Key Laboratory of Bone & Cartilage Regenerative Medicine, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, PR China.
Abstract
AIM: This study aimed to investigate the values of preoperative serum levels of white blood cell, erythrocyte sedimentation rate (ESR), C-reactive protein, procalcitonin, IL-6, TNF-α and serum amyloid A for diagnosis of chronic osteomyelitis (COM) in Chinese patients. METHODS: All 586 eligible patients were included for analysis. RESULTS: Outcomes revealed that positive ratios of TNF-α, ESR and IL-6 lied in top three. Taken predicted probability and detection cost into consideration, combination of ESR, IL-6 and TNF-α might be the optimal model due to its high predicted probability for COM (91.02%) with an acceptable cost (CN¥161). CONCLUSION: Combination of preoperative serum TNF-α, ESR and IL-6 can help a reliable predication of COM.
AIM: This study aimed to investigate the values of preoperative serum levels of white blood cell, erythrocyte sedimentation rate (ESR), C-reactive protein, procalcitonin, IL-6, TNF-α and serum amyloid A for diagnosis of chronic osteomyelitis (COM) in Chinese patients. METHODS: All 586 eligible patients were included for analysis. RESULTS: Outcomes revealed that positive ratios of TNF-α, ESR and IL-6 lied in top three. Taken predicted probability and detection cost into consideration, combination of ESR, IL-6 and TNF-α might be the optimal model due to its high predicted probability for COM (91.02%) with an acceptable cost (CN¥161). CONCLUSION: Combination of preoperative serum TNF-α, ESR and IL-6 can help a reliable predication of COM.
Authors: Paul Bosch; Janna van den Kieboom; Joost D J Plate; Frank F A IJpma; R Marijn Houwert; Albert Huisman; Falco Hietbrink; Luke P H Leenen; Geertje A M Govaert Journal: J Bone Jt Infect Date: 2018-07-06
Authors: Maria Imaculada de Queiroz Rodrigues; Joyce Ohana de Lima Martins; Paulo Goberlânio de Barros Silva; Antônio Ernando Carlos Ferreira Júnior; Maria Elisa Quezado Lima Verde; Fabrício Bitú Sousa; Mário Rogério Lima Mota; Ana Paula Negreiros Nunes Alves Journal: J Oral Maxillofac Surg Date: 2020-08-15 Impact factor: 1.895