STUDY OF CHLOROQUINE RESISTANCE IN Plasmodium falciparum INFECTION IN NORTH EAST INDIA.

During the period April 1993 to July 1993, a total of 410 patients with pyrexia were screened for malarial parasite and 109 (26.5%) cases were found positive for malarial parasite. Of these 109 cases, 91 were positive for Plasmodium falciparum. Of these 91 cases, 43 patients fulfilled the study criteria as per WHO's extended field trial and were included in the analysis. These patients were treated with standard doses of chloroquine. Seven patients each (16.3%) showed RI and RII resistance and 2 patients (4.7%) showed RIII levels of chloroquine resistance.