Literature DB >> 28769196

PULMONARY LESIONS ASSOCIATED WITH BLEOMYCIN THERAPY IN MALIGNANCIES.

J R Bhardwaj1, K Kartik2, S Sambandam3.   

Abstract

Pulmonary lesions in seven patients with malignancy who were treated with bleomycin were studied at autopsy. Six of them had symptoms of respiratory distress. The lesions showed a predilection for the lower lobe and subpleural zones. Diffuse alveolar damage progressing to interstitial pneumonitis at varying stages of evolution was observed in all cases. The changes included intra-alveolar proteinaceous exudate, extensive interstitial fibrosis and frank epithelial dysplasia simulating metastatic nodules.

Entities:  

Keywords:  Bleomycin; Diffuse alveolar damage; Interstitial pneumonitis

Year:  2017        PMID： 28769196      PMCID： PMC5529761          DOI： 10.1016/S0377-1237(17)31052-3

Source DB:  PubMed          Journal:  Med J Armed Forces India        ISSN： 0377-1237


  10 in total

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Authors:  A L Horowitz; M Friedman; J Smith; A Yagoda; C LaMonte; R C Watson
Journal:  Radiology       Date:  1973-01       Impact factor: 11.105

2.  Interstitial pneumonitis associated with bleomycin therapy.

Authors:  M A Luna; C W Bedrossian; B Lichtiger; P A Salem
Journal:  Am J Clin Pathol       Date:  1972-11       Impact factor: 2.493

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Authors:  Y Shimosato; K Baba; S Watanabe
Journal:  Gan No Rinsho       Date:  1971

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Authors:  H Umezawa; M Ishizuka; K Maeda; T Takeuchi
Journal:  Cancer       Date:  1967-05       Impact factor: 6.860

5.  Early diagnosis of bleomycin pulmonary toxicity using bronchoalveolar lavage in dogs.

Authors:  P J Fahey; M J Utell; R J Mayewski; J D Wandtke; R W Hyde
Journal:  Am Rev Respir Dis       Date:  1982-07

Review 6.  Immunosuppressive and cytotoxic chemotherapy: long-term complications.

Authors:  P S Schein; S H Winokur
Journal:  Ann Intern Med       Date:  1975-01       Impact factor: 25.391

7.  Drug-related pulmonary toxicity in non-Hodgkin's lymphoma. Comparative results with three different treatment regimens.

Authors:  C L Shapiro; B Y Yeap; J Godleski; M S Jochelson; M A Shipp; A T Skarin; G P Canellos
Journal:  Cancer       Date:  1991-08-15       Impact factor: 6.860

8.  Study of the clinical efficiency of bleomycin in human cancer.

Authors: 
Journal:  Br Med J       Date:  1970-06-13

9.  Bleomycin toxicity simulating metastatic nodules to the lungs.

Authors:  E S McCrea; J N Diaconis; J C Wade; C A Johnston
Journal:  Cancer       Date:  1981-09-01       Impact factor: 6.860

10.  Combination chemotherapy of advanced non-Hodgkin lymphoma with bleomycin, adriamycin, cyclophosphamide, vincristine, and prednisone (BACOP).

Authors:  A T Skarin; D S Rosenthal; W C Moloney; E Frei
Journal:  Blood       Date:  1977-05       Impact factor: 22.113
  10 in total

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