Literature DB >> 28767774

Factors associated with malnutrition in adolescent and adult patients with cystic fibrosis.

Gabriela Cristofoli Barni1, Gabriele Carra Forte1, Luis Felipe Forgiarini1,2, Claudine Lacerda de Oliveira Abrahão3, Paulo de Tarso Roth Dalcin1,4.   

Abstract

OBJECTIVE: To determine the prevalence of malnutrition in patients attending an adult cystic fibrosis (CF) program and to investigate the associations of malnutrition with the clinical characteristics of those patients.
METHODS: This was a cross-sectional study involving patients with clinically stable CF patients (16 years of age or older). The patients underwent clinical assessment, nutritional assessments, pulmonary function tests, and pancreatic function assessment. They also completed a questionnaire regarding diet compliance. On the basis of their nutritional status, the patients were classified divided into three groups: adequate nutrition; at nutritional risk; and malnutrition.
RESULTS: The study has included 73 patients (mean age, 25.6 ± 7.3 years), 40 of whom (54.8%) were female. The mean body mass index was 21.0 ± 3.0 kg/m2 and the mean FEV1 was 59.7 ± 30.6% of predicted. In this sample of patients, 32 (43.8%), 23 (31.5%), and 18 (24.7%) of the patients were allocated to the adequate nutrition, nutritional risk, and malnutrition groups, respectively. The logistic regression analysis identified three independent factors associated with the risk of malnutrition: Shwachman-Kulczycki score, percent predicted FEV1; and age.
CONCLUSIONS: Malnutrition remains a common complication in adolescents and adults with CF, despite dietary advice. Malnutrition is associated with age, clinical severity, and lung function impairment.

Entities:  

Mesh:

Year:  2017        PMID: 28767774     DOI: 10.1590/S1806-37562016000000319

Source DB:  PubMed          Journal:  J Bras Pneumol        ISSN: 1806-3713            Impact factor:   2.624


  5 in total

1.  Low body mass index as a barrier to lung transplant in cystic fibrosis.

Authors:  Ann L Jennerich; Joseph B Pryor; Travis Y Hee Wai; Siddhartha G Kapnadak; Moira L Aitken; Christopher H Goss; Kathleen J Ramos
Journal:  J Cyst Fibros       Date:  2021-12-23       Impact factor: 5.527

2.  Underweight Patients With Cystic Fibrosis Have Acceptable Survival Following Lung Transplantation: A United Network for Organ Sharing Registry Study.

Authors:  Kathleen J Ramos; Siddhartha G Kapnadak; Miranda C Bradford; Ranjani Somayaji; Eric D Morrell; Joseph M Pilewski; Erika D Lease; Michael S Mulligan; Moira L Aitken; Cynthia J Gries; Christopher H Goss
Journal:  Chest       Date:  2020-01-17       Impact factor: 9.410

3.  BODY MASS INDEX AND ALBUMIN LEVELS ARE ASSOCIATED WITH PULMONARY FUNCTION PARAMETERS IN PEDIATRIC SUBJECTS WITH CYSTIC FIBROSIS.

Authors:  Miriam Isabel Souza Dos Santos Simon; Gabriele Carra Forte; Paulo José Cauduro Marostica
Journal:  Rev Paul Pediatr       Date:  2019-05-09

4.  Triage for Malnutrition Risk among Pediatric and Adolescent Outpatients with Cystic Fibrosis, Using a Disease-Specific Tool.

Authors:  Dimitrios Poulimeneas; Maria G Grammatikopoulou; Argyri Petrocheilou; Athanasios G Kaditis; Tonia Vassilakou
Journal:  Children (Basel)       Date:  2020-12-04

5.  Association of Body Mass Index With Clinical Outcomes in Patients With Cystic Fibrosis: A Systematic Review and Meta-analysis.

Authors:  Rita Nagy; Noémi Gede; Klementina Ocskay; Bernadett-Miriam Dobai; Alan Abada; Zsófia Vereczkei; Piroska Pázmány; Dorottya Kató; Péter Hegyi; Andrea Párniczky
Journal:  JAMA Netw Open       Date:  2022-03-01
  5 in total

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