Literature DB >> 28765369

Role of clusterin in the brain vascular clearance of amyloid-β.

Amy R Nelson1,2, Abhay P Sagare1,2, Berislav V Zlokovic3,2.   

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Year:  2017        PMID: 28765369      PMCID: PMC5565473          DOI: 10.1073/pnas.1711357114

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN: 0027-8424            Impact factor:   11.205


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  23 in total

1.  Interaction of apolipoprotein J-amyloid beta-peptide complex with low density lipoprotein receptor-related protein-2/megalin. A mechanism to prevent pathological accumulation of amyloid beta-peptide.

Authors:  S M Hammad; S Ranganathan; E Loukinova; W O Twal; W S Argraves
Journal:  J Biol Chem       Date:  1997-07-25       Impact factor: 5.157

2.  Apolipoprotein E markedly facilitates age-dependent cerebral amyloid angiopathy and spontaneous hemorrhage in amyloid precursor protein transgenic mice.

Authors:  John D Fryer; Jennie W Taylor; Ronald B DeMattos; Kelly R Bales; Steven M Paul; Maia Parsadanian; David M Holtzman
Journal:  J Neurosci       Date:  2003-08-27       Impact factor: 6.167

3.  Glycoprotein 330/megalin: probable role in receptor-mediated transport of apolipoprotein J alone and in a complex with Alzheimer disease amyloid beta at the blood-brain and blood-cerebrospinal fluid barriers.

Authors:  B V Zlokovic; C L Martel; E Matsubara; J G McComb; G Zheng; R T McCluskey; B Frangione; J Ghiso
Journal:  Proc Natl Acad Sci U S A       Date:  1996-04-30       Impact factor: 11.205

4.  Loss of clusterin shifts amyloid deposition to the cerebrovasculature via disruption of perivascular drainage pathways.

Authors:  Aleksandra M Wojtas; Silvia S Kang; Benjamin M Olley; Maureen Gatherer; Mitsuru Shinohara; Patricia A Lozano; Chia-Chen Liu; Aishe Kurti; Kelsey E Baker; Dennis W Dickson; Mei Yue; Leonard Petrucelli; Guojun Bu; Roxana O Carare; John D Fryer
Journal:  Proc Natl Acad Sci U S A       Date:  2017-07-12       Impact factor: 11.205

5.  Characterization of amyloid deposition in the APPswe/PS1dE9 mouse model of Alzheimer disease.

Authors:  Monica Garcia-Alloza; Elissa M Robbins; Sandy X Zhang-Nunes; Susan M Purcell; Rebecca A Betensky; Susan Raju; Claudia Prada; Steven M Greenberg; Brian J Bacskai; Matthew P Frosch
Journal:  Neurobiol Dis       Date:  2006-10-05       Impact factor: 5.996

6.  Clusterin facilitates in vivo clearance of extracellular misfolded proteins.

Authors:  Amy R Wyatt; Justin J Yerbury; Paula Berghofer; Ivan Greguric; Andrew Katsifis; Christopher M Dobson; Mark R Wilson
Journal:  Cell Mol Life Sci       Date:  2011-04-20       Impact factor: 9.261

7.  Clearance of Alzheimer's amyloid-ss(1-40) peptide from brain by LDL receptor-related protein-1 at the blood-brain barrier.

Authors:  M Shibata; S Yamada; S R Kumar; M Calero; J Bading; B Frangione; D M Holtzman; C A Miller; D K Strickland; J Ghiso; B V Zlokovic
Journal:  J Clin Invest       Date:  2000-12       Impact factor: 14.808

8.  Brain uptake of circulating apolipoproteins J and E complexed to Alzheimer's amyloid beta.

Authors:  B V Zlokovic; C L Martel; J B Mackic; E Matsubara; T Wisniewski; J G McComb; B Frangione; J Ghiso
Journal:  Biochem Biophys Res Commun       Date:  1994-12-15       Impact factor: 3.575

9.  Clusterin promotes amyloid plaque formation and is critical for neuritic toxicity in a mouse model of Alzheimer's disease.

Authors:  Ronald B DeMattos; Mark A O'dell; Maia Parsadanian; Jennie W Taylor; Judith A K Harmony; Kelly R Bales; Steven M Paul; Bruce J Aronow; David M Holtzman
Journal:  Proc Natl Acad Sci U S A       Date:  2002-07-26       Impact factor: 11.205

10.  Central role for PICALM in amyloid-β blood-brain barrier transcytosis and clearance.

Authors:  Zhen Zhao; Abhay P Sagare; Qingyi Ma; Matthew R Halliday; Pan Kong; Kassandra Kisler; Ethan A Winkler; Anita Ramanathan; Takahisa Kanekiyo; Guojun Bu; Nelly Chuqui Owens; Sanket V Rege; Gabriel Si; Ashim Ahuja; Donghui Zhu; Carol A Miller; Julie A Schneider; Manami Maeda; Takahiro Maeda; Tohru Sugawara; Justin K Ichida; Berislav V Zlokovic
Journal:  Nat Neurosci       Date:  2015-05-25       Impact factor: 24.884

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  31 in total

Review 1.  Breakdown of the blood-brain barrier: A mediator of increased Alzheimer's risk in patients with metabolic disorders?

Authors:  Corey J Frank; Ewan C McNay
Journal:  J Neuroendocrinol       Date:  2021-12-13       Impact factor: 3.627

Review 2.  Cerebrovascular phenotypes in mouse models of Alzheimer's disease.

Authors:  Jenny I Szu; André Obenaus
Journal:  J Cereb Blood Flow Metab       Date:  2021-02-08       Impact factor: 6.200

Review 3.  Peripheral Pathways to Neurovascular Unit Dysfunction, Cognitive Impairment, and Alzheimer's Disease.

Authors:  Amy R Nelson
Journal:  Front Aging Neurosci       Date:  2022-04-18       Impact factor: 5.702

4.  Relation of plasma β-amyloid, clusterin, and tau with cerebral microbleeds: Framingham Heart Study.

Authors:  José Rafael Romero; Serkalem Demissie; Alexa Beiser; Jayandra J Himali; Charles DeCarli; Daniel Levy; Sudha Seshadri
Journal:  Ann Clin Transl Neurol       Date:  2020-06-26       Impact factor: 4.511

5.  Single-cell RNA sequencing identifies senescent cerebromicrovascular endothelial cells in the aged mouse brain.

Authors:  Tamas Kiss; Ádám Nyúl-Tóth; Priya Balasubramanian; Stefano Tarantini; Chetan Ahire; Jordan DelFavero; Andriy Yabluchanskiy; Tamas Csipo; Eszter Farkas; Graham Wiley; Lori Garman; Anna Csiszar; Zoltan Ungvari
Journal:  Geroscience       Date:  2020-03-31       Impact factor: 7.713

Review 6.  Beyond the neuron-cellular interactions early in Alzheimer disease pathogenesis.

Authors:  Christopher M Henstridge; Bradley T Hyman; Tara L Spires-Jones
Journal:  Nat Rev Neurosci       Date:  2019-02       Impact factor: 34.870

Review 7.  Vascular contributions to cognitive impairment and dementia: the emerging role of 20-HETE.

Authors:  Ezekiel Gonzalez-Fernandez; Yedan Liu; Alexander P Auchus; Fan Fan; Richard J Roman
Journal:  Clin Sci (Lond)       Date:  2021-08-13       Impact factor: 6.876

8.  Characterization of ApoJ-reconstituted high-density lipoprotein (rHDL) nanodisc for the potential treatment of cerebral β-amyloidosis.

Authors:  Sofía Fernández-de-Retana; Mary Cano-Sarabia; Paula Marazuela; Jose Luis Sánchez-Quesada; Annabel Garcia-Leon; Alex Montañola; Joan Montaner; Daniel Maspoch; Mar Hernández-Guillamon
Journal:  Sci Rep       Date:  2017-11-07       Impact factor: 4.379

Review 9.  Immunotherapy of Mild Cognitive Impairment by ω-3 Supplementation: Why Are Amyloid-β Antibodies and ω-3 Not Working in Clinical Trials?

Authors:  Milan Fiala; Lucas Restrepo; Matteo Pellegrini
Journal:  J Alzheimers Dis       Date:  2018       Impact factor: 4.472

10.  Diverse Protein Profiles in CNS Myeloid Cells and CNS Tissue From Lipopolysaccharide- and Vehicle-Injected APPSWE/PS1ΔE9 Transgenic Mice Implicate Cathepsin Z in Alzheimer's Disease.

Authors:  Camilla Thygesen; Laura Ilkjær; Stefan J Kempf; Anne Louise Hemdrup; Christian Ulrich von Linstow; Alicia A Babcock; Sultan Darvesh; Martin R Larsen; Bente Finsen
Journal:  Front Cell Neurosci       Date:  2018-11-06       Impact factor: 5.505

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