Literature DB >> 28765187

Non-atherosclerotic aortic mural thrombus: a rare source of embolism.

Julian A Marin-Acevedo1, Andree H Koop1, Jose L Diaz-Gomez2, Pramod K Guru2.   

Abstract

A 54-year-old man presented to the emergency department with acute left-sided chest pain and left upper quadrant abdominal pain. He had a significant history of squamous cell carcinoma of the lung previously treated with right pneumonectomy who ; is currently receiving adjuvant chemotherapy with cisplatin. Physical examination was remarkable for tachycardia, hypertension and mild abdominal tenderness. CT angiography revealed an aortic mural thrombus in the ascending aorta and aortic arch without dissection, aneurysm or tortuosity of the aorta. In addition, an infarction of the inferior spleen was reported. Given the high risk of surgery for this patient, he was treated conservatively with esmolol and heparin infusion. His subsequent hospital course was uneventful, and he was successfully discharged on enoxaparin therapy that was successively bridged to rivaroxaban treatment. Follow-up transesophageal echocardiography and CT angiography at one month showed no thrombus in the aorta. © BMJ Publishing Group Ltd (unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

Entities:  

Keywords:  chemotherapy; lung cancer (oncology)

Mesh:

Substances:

Year:  2017        PMID: 28765187      PMCID: PMC5623256          DOI: 10.1136/bcr-2017-220592

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN: 1757-790X


  22 in total

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Journal:  Echocardiography       Date:  2003-02       Impact factor: 1.724

2.  Successful thrombolysis of an aortic-arch thrombus in a patient after mesenteric embolism.

Authors:  D Hausmann; D Gulba; K Bargheer; J Niedermeyer; K A Comess; W G Daniel
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3.  Incidental discovery of an ascending aortic thrombus: should this patient undergo surgical intervention?

Authors:  Subhasis Chatterjee; Susan S Eagle; David H Adler; John G Byrne
Journal:  J Thorac Cardiovasc Surg       Date:  2009-08-18       Impact factor: 5.209

4.  Risk factors for deep vein thrombosis and pulmonary embolism: a population-based case-control study.

Authors:  J A Heit; M D Silverstein; D N Mohr; T M Petterson; W M O'Fallon; L J Melton
Journal:  Arch Intern Med       Date:  2000-03-27

5.  Mural aortic thrombi: An important cause of peripheral embolization.

Authors:  P U Reber; A G Patel; E Stauffer; M F Müller; D D Do; H W Kniemeyer
Journal:  J Vasc Surg       Date:  1999-12       Impact factor: 4.268

6.  Prospective evaluation of major vascular events in patients with nonsmall cell lung carcinoma treated with cisplatin and gemcitabine.

Authors:  Gianmauro Numico; Ornella Garrone; Vincenzo Dongiovanni; Nicola Silvestris; Ida Colantonio; Gianna Di Costanzo; Cristina Granetto; Marcella Occelli; Elena Fea; Abdelamid Heouaine; Milena Gasco; Marco Merlano
Journal:  Cancer       Date:  2005-03-01       Impact factor: 6.860

7.  Acute aortic thrombosis in patients receiving cisplatin-based chemotherapy.

Authors:  D D Fernandes; M L Louzada; C A Souza; F Matzinger
Journal:  Curr Oncol       Date:  2011-04       Impact factor: 3.677

8.  Anticoagulation is an effective treatment for aortic mural thrombi.

Authors:  Michael E Bowdish; Fred A Weaver; Howard A Liebman; Vincent L Rowe; Douglas B Hood
Journal:  J Vasc Surg       Date:  2002-10       Impact factor: 4.268

9.  Treatment-specific risks of second malignancies and cardiovascular disease in 5-year survivors of testicular cancer.

Authors:  Alexandra W van den Belt-Dusebout; Ronald de Wit; Jourik A Gietema; Simon Horenblas; Marieke W J Louwman; Jacques G Ribot; Harald J Hoekstra; Gabey M Ouwens; Berthe M P Aleman; Flora E van Leeuwen
Journal:  J Clin Oncol       Date:  2007-10-01       Impact factor: 44.544

10.  A hanging mass in the ascending aorta diagnosed by transthoracic echocardiography in a totally asymptomatic subject.

Authors:  Umberto Baldini; Francesca Chiaramonti; Gaetano Minzioni; Michele Galli
Journal:  J Am Soc Echocardiogr       Date:  2009-10       Impact factor: 5.251

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  2 in total

1.  Direct oral anticoagulant therapy as an alternative to surgery for the treatment of a patient with a floating thrombus in the ascending aorta and pulmonary embolism.

Authors:  Masashi Toyama; Masato Nakayama; Masahiko Hasegawa; Takeshi Yuasa; Bunmei Sato; Osamu Ohno
Journal:  J Vasc Surg Cases Innov Tech       Date:  2018-04-30

2.  Large de novo ascending aortic thrombus successfully treated with anticoagulation.

Authors:  Mustafa Houmsse; Asia McDavid; Ahmet Kilic
Journal:  J Cardiovasc Thorac Res       Date:  2018-05-21
  2 in total

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