| Literature DB >> 28764183 |
Sushma Nayar1, Kishore Babu Esakkimuthu Parvathi2, Mayilananthi Kaliannan3, Premlatha Sivasailam4.
Abstract
Acquired coagulation factor VIII inhibitor leads to a rare disease i.e., acquired haemophilia which is idiopathic in majority of cases and is seen with autoimmune diseases, haematologic and solid tumours, infections, in the post-partum period and also with certain long-term use of drugs like penicillin and its derivatives, phenytoin, sulfa antibiotics, chloramphenicol, methyldopa, chlorpromazine, levodopa, interferon-α, fludarabine, clopidogrel. We report a case here, with acquired Factor VIII (FVIII) inhibitor acquisition which presented with delayed wound healing as a result of protracted bleeding into the wound. The inhibitor was acquired due to prolonged chlorpromazine use.Entities:
Keywords: Chlorpromazine; Idiopathic; Protracted bleeding
Year: 2017 PMID: 28764183 PMCID: PMC5535376 DOI: 10.7860/JCDR/2017/21598.10109
Source DB: PubMed Journal: J Clin Diagn Res ISSN: 0973-709X