PURPOSE: The purpose of this study was to identify the size criteria of lateral lymph node metastasis in lower rectal cancer both in patients who underwent preoperative CRT and those who did not. METHODS: This study enrolled 150 patients who underwent resection for primary lower rectal adenocarcinoma with lateral lymph node dissection between 2013 and 2015. Patients were divided into two groups: the CRT group, treated with preoperative chemoradiotherapy before surgery, and the non-CRT group, treated with surgery alone. The short-axis diameter of each dissected lateral lymph node was measured. Receiver-operating characteristic curves were generated to reveal the optimal cutoff values for determining lateral lymph node metastasis in both groups. RESULTS: In the non-CRT group (n = 131), the ROC curve demonstrated that the optimal cutoff value for determining metastasis was 6.0 mm, with a sensitivity of 78.5% and specificity of 82.9%, and the AUC was 0.845. In comparison, in the CRT group (n = 19), the optimal cutoff value was 5.0 mm, with a sensitivity of 71.4% and specificity of 85.3% and an AUC of 0.836. CONCLUSION: The cutoff size for determining lateral lymph node metastasis was smaller in the CRT group than in the non-CRT group.
PURPOSE: The purpose of this study was to identify the size criteria of lateral lymph node metastasis in lower rectal cancer both in patients who underwent preoperative CRT and those who did not. METHODS: This study enrolled 150 patients who underwent resection for primary lower rectal adenocarcinoma with lateral lymph node dissection between 2013 and 2015. Patients were divided into two groups: the CRT group, treated with preoperative chemoradiotherapy before surgery, and the non-CRT group, treated with surgery alone. The short-axis diameter of each dissected lateral lymph node was measured. Receiver-operating characteristic curves were generated to reveal the optimal cutoff values for determining lateral lymph node metastasis in both groups. RESULTS: In the non-CRT group (n = 131), the ROC curve demonstrated that the optimal cutoff value for determining metastasis was 6.0 mm, with a sensitivity of 78.5% and specificity of 82.9%, and the AUC was 0.845. In comparison, in the CRT group (n = 19), the optimal cutoff value was 5.0 mm, with a sensitivity of 71.4% and specificity of 85.3% and an AUC of 0.836. CONCLUSION: The cutoff size for determining lateral lymph node metastasis was smaller in the CRT group than in the non-CRT group.
Authors: Seok-Byung Lim; Chang Sik Yu; Chan Wook Kim; Yong Sik Yoon; Seong Ho Park; Tae Won Kim; Jong Hoon Kim; Jin Cheon Kim Journal: Int J Colorectal Dis Date: 2013-08-14 Impact factor: 2.571
Authors: Niki Christou; Jeremy Meyer; Christophe Combescure; Alexandre Balaphas; Joan Robert-Yap; Nicolas C Buchs; Frédéric Ris Journal: World J Surg Date: 2021-02-04 Impact factor: 3.352
Authors: Miriam K Rutegård; Malin Båtsman; Lennart Blomqvist; Martin Rutegård; Jan Axelsson; Ingrid Ljuslinder; Jörgen Rutegård; Richard Palmqvist; Fredrik Brännström; Patrik Brynolfsson; Katrine Riklund Journal: Cancer Imaging Date: 2020-10-31 Impact factor: 3.909