| Literature DB >> 28761992 |
Jamshid H Karimov1, Shengqiang Gao2, Raymond Dessoffy3, Gengo Sunagawa3, Martin Sinkewich4, Patrick Grady4, Shiva Sale5, Nader Moazami3,6, Kiyotaka Fukamachi7.
Abstract
Successful implantation of a total artificial heart relies on multiple standardized procedures, primarily the resection of the native heart, and exacting preparation of the atrial and vascular conduits for pump implant and activation. Achieving secure pump connections to inflow/outflow conduits is critical to a successful outcome. During the connection process, however, air may be introduced into the circulation, traveling to the brain and multiple organs. Such air emboli block blood flow to these areas and are detrimental to long-term survival. A correctly managed pump-to-conduit connection prevents air from collecting in the pump and conduits. To further optimize pump-connection techniques, we have developed a novel connecting sleeve that enables airless connection of the Cleveland Clinic continuous-flow total artificial heart (CFTAH) to the conduits. In this brief report, we describe the connecting sleeve design and our initial results from two acute in vivo implantations using a scaled-down version of the CFTAH.Entities:
Keywords: Air embolism; Artificial heart; Circulation assisted; Deairing techniques; Pump connection
Mesh:
Year: 2017 PMID: 28761992 DOI: 10.1007/s10047-017-0976-3
Source DB: PubMed Journal: J Artif Organs ISSN: 1434-7229 Impact factor: 1.731