Literature DB >> 28761992

Novel technique for airless connection of artificial heart to vascular conduits.

Jamshid H Karimov1, Shengqiang Gao2, Raymond Dessoffy3, Gengo Sunagawa3, Martin Sinkewich4, Patrick Grady4, Shiva Sale5, Nader Moazami3,6, Kiyotaka Fukamachi7.   

Abstract

Successful implantation of a total artificial heart relies on multiple standardized procedures, primarily the resection of the native heart, and exacting preparation of the atrial and vascular conduits for pump implant and activation. Achieving secure pump connections to inflow/outflow conduits is critical to a successful outcome. During the connection process, however, air may be introduced into the circulation, traveling to the brain and multiple organs. Such air emboli block blood flow to these areas and are detrimental to long-term survival. A correctly managed pump-to-conduit connection prevents air from collecting in the pump and conduits. To further optimize pump-connection techniques, we have developed a novel connecting sleeve that enables airless connection of the Cleveland Clinic continuous-flow total artificial heart (CFTAH) to the conduits. In this brief report, we describe the connecting sleeve design and our initial results from two acute in vivo implantations using a scaled-down version of the CFTAH.

Entities:  

Keywords:  Air embolism; Artificial heart; Circulation assisted; Deairing techniques; Pump connection

Mesh:

Year:  2017        PMID: 28761992     DOI: 10.1007/s10047-017-0976-3

Source DB:  PubMed          Journal:  J Artif Organs        ISSN: 1434-7229            Impact factor:   1.731


  5 in total

1.  Deairing Techniques for Double-Ended Centrifugal Total Artificial Heart Implantation.

Authors:  Jamshid H Karimov; David J Horvath; Nicole Byram; Gengo Sunagawa; Patrick Grady; Martin Sinkewich; Nader Moazami; Shiva Sale; Leonard A R Golding; Kiyotaka Fukamachi
Journal:  Artif Organs       Date:  2016-09-22       Impact factor: 3.094

2.  Effects of mechanical ventilation with normobaric oxygen therapy on the rate of air removal from cerebral arteries.

Authors:  D Annane; G Troché; F Delisle; P Devauchelle; F Paraire; J C Raphaël; P Gajdos
Journal:  Crit Care Med       Date:  1994-05       Impact factor: 7.598

3.  The significance and prevention of air emboli with the total artificial heart.

Authors:  K D Murray; P F Binkley; D A Dumond; K M Watson; E P Howanitz; P Ross; P D Myerowitz
Journal:  Artif Organs       Date:  1993-08       Impact factor: 3.094

4.  An innovative, sensorless, pulsatile, continuous-flow total artificial heart: device design and initial in vitro study.

Authors:  Kiyotaka Fukamachi; David J Horvath; Alex L Massiello; Hideyuki Fumoto; Tetsuya Horai; Santosh Rao; Leonard A R Golding
Journal:  J Heart Lung Transplant       Date:  2009-09-26       Impact factor: 10.247

5.  The Cleveland Clinic-Nimbus total artificial heart. In vivo hemodynamic performance in calves and preclinical studies.

Authors:  P M McCarthy; K Fukamachi; F Fukumura; K Muramoto; L A Golding; H Harasaki
Journal:  J Thorac Cardiovasc Surg       Date:  1994-09       Impact factor: 5.209

  5 in total

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