Literature DB >> 28761545

Primary pleomorphic xanthoastrocytoma of the spinal cord: A case report and review of literature.

Mayur Sharma1, Vernon Velho1, Rachana Binayake2, Hrushikesh Kharosekar1.   

Abstract

Primary pleomorphic xanthoastrocytoma (PXA) of the spinal cord is a rare slow growing tumor. To our knowledge, only five such cases have been reported in the literature till date. We report the clinical, radiological, and histopathological features of a spinal PXA in a 23-year-old female previously operated 5 years back for a spinal tumor, presented with weakness in lower limbs, sphincter incontinence and low back pain. Magnetic resonance imaging scan with contrast reveals an intramedullary lesion in the spinal cord from D8-D10 level. The patient was operated with reexploration of the previous incision, and gross total excision was achieved. Histopathology confirmed the diagnosis of PXA. Clinical and radiological follow-up is required to detect early recurrence. Adjunct radiotherapy or and chemotherapy should be considered only when there is postoperative residual or recurrence, however there are no definite guidelines in view of the rarity of this condition.

Entities:  

Keywords:  Pleomorphic; primary; spinal; xanthoastrocytoma

Year:  2017        PMID: 28761545      PMCID: PMC5532952          DOI: 10.4103/1793-5482.145547

Source DB:  PubMed          Journal:  Asian J Neurosurg


  11 in total

1.  Pleomorphic xanthoastrocytoma: what do we really know about it?

Authors:  C Giannini; B W Scheithauer; P C Burger; D J Brat; P C Wollan; B Lach; B P O'Neill
Journal:  Cancer       Date:  1999-05-01       Impact factor: 6.860

2.  Primary spinal pleomorphic xanthoastrocytoma.

Authors:  Maneet Gill; H C Pathak; Renu Madan; S Bhattacharya; G S Choudhary
Journal:  Neurol India       Date:  2010 Sep-Oct       Impact factor: 2.117

3.  Pleomorphic xanthoastrocytoma of the spinal cord. Case report.

Authors:  Masaya Nakamura; Kazuhiro Chiba; Morio Matsumoto; Eij Ikeda; Yoshiaki Toyama
Journal:  J Neurosurg Spine       Date:  2006-07

4.  Pleomorphic xanthoastrocytoma: favorable outcome after complete surgical resection.

Authors:  M Fouladi; J Jenkins; P Burger; J Langston; T Merchant; R Heideman; S Thompson; A Sanford; L Kun; A Gajjar
Journal:  Neuro Oncol       Date:  2001-07       Impact factor: 12.300

Review 5.  Pleomorphic xanthoastrocytoma - a clinico-pathological review.

Authors:  Aman Sharma; Daya Nand Sharma; Parmod Kumar Julka; Goura Kishor Rath
Journal:  Neurol Neurochir Pol       Date:  2011 Jul-Aug       Impact factor: 1.621

6.  Pleomorphic xanthoastrocytoma in the spinal cord. Case report.

Authors:  M J Herpers; G Freling; E A Beuls
Journal:  J Neurosurg       Date:  1994-03       Impact factor: 5.115

Review 7.  Clinical, radiological, and therapeutic features of pleomorphic xanthoastrocytoma: report of three patients and review of the literature.

Authors:  D van Roost; R Kristof; J Zentner; H K Wolf; J Schramm
Journal:  J Neurol Neurosurg Psychiatry       Date:  1996-06       Impact factor: 10.154

8.  Pleomorphic xanthoastrocytoma: a distinctive meningocerebral glioma of young subjects with relatively favorable prognosis. A study of 12 cases.

Authors:  J J Kepes; L J Rubinstein; L F Eng
Journal:  Cancer       Date:  1979-11       Impact factor: 6.860

Review 9.  Primary anaplastic pleomorphic xanthoastrocytoma with widespread neuroaxis dissemination at diagnosis--a pediatric case report and review of the literature.

Authors:  Toshiyuki Okazaki; Teruyoshi Kageji; Kazuhito Matsuzaki; Hidehisa Horiguchi; Takanori Hirose; Hiroyoshi Watanabe; Toshihiro Ohnishi; Shinji Nagahiro
Journal:  J Neurooncol       Date:  2009-03-27       Impact factor: 4.130

10.  Pleomorphic xanthoastrocytoma. Ultrastructural, immunohistochemical, and DNA cytofluorometric study of a case.

Authors:  Y Hosokawa; Y Tsuchihashi; H Okabe; M Toyama; K Namura; M Kuga; T Yonezawa; S Fujita; T Ashihara
Journal:  Cancer       Date:  1991-08-15       Impact factor: 6.860

View more
  1 in total

1.  Intradural extramedullary pleomorphic xanthoastrocytoma: A case report.

Authors:  Daniel R Klinger; Rebecca L Dillon; Nathan F Clement; Francis J Cloran; Iren Horkayne-Szakaly
Journal:  Surg Neurol Int       Date:  2020-10-29
  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.