Literature DB >> 28760626

How do the brain's time and space mediate consciousness and its different dimensions? Temporo-spatial theory of consciousness (TTC).

Georg Northoff1, Zirui Huang2.   

Abstract

Time and space are the basic building blocks of nature. As a unique existent in nature, our brain exists in time and takes up space. The brain's activity itself also constitutes and spreads in its own (intrinsic) time and space that is crucial for consciousness. Consciousness is a complex phenomenon including different dimensions: level/state, content/form, phenomenal aspects, and cognitive features. We propose a Temporo-spatial Theory of Consciousness (TTC) focusing primarily on the temporal and spatial features of the brain activity. We postulate four different neuronal mechanisms accounting for the different dimensions of consciousness: (i) "temporo-spatial nestedness" of the spontaneous activity accounts for the level/state of consciousness as neural predisposition of consciousness (NPC); (ii) "temporo-spatial alignment" of the pre-stimulus activity accounts for the content/form of consciousness as neural prerequisite of consciousness (preNCC); (iii) "temporo-spatial expansion" of early stimulus-induced activity accounts for phenomenal consciousness as neural correlates of consciousness (NCC); (iv) "temporo-spatial globalization" of late stimulus-induced activity accounts for the cognitive features of consciousness as neural consequence of consciousness (NCCcon).
Copyright © 2017 Elsevier Ltd. All rights reserved.

Keywords:  Consciousness; Cross-frequency coupling; Frequency nestedness; Infra-slow fluctuations; Phenomenology; Pre-stimulus activity; Qualia; Scale-free; Small-world; Space; Spontaneous activity; Time

Mesh:

Year:  2017        PMID: 28760626     DOI: 10.1016/j.neubiorev.2017.07.013

Source DB:  PubMed          Journal:  Neurosci Biobehav Rev        ISSN: 0149-7634            Impact factor:   8.989


  38 in total

1.  Disruption of Conscious Access in Psychosis Is Associated with Altered Structural Brain Connectivity.

Authors:  Lucie Berkovitch; Lucie Charles; Antoine Del Cul; Nora Hamdani; Marine Delavest; Samuel Sarrazin; Jean-François Mangin; Pamela Guevara; Ellen Ji; Marc-Antoine d'Albis; Raphaël Gaillard; Frank Bellivier; Cyril Poupon; Marion Leboyer; Ryad Tamouza; Stanislas Dehaene; Josselin Houenou
Journal:  J Neurosci       Date:  2020-11-23       Impact factor: 6.167

2.  BOLD temporal variability differentiates wakefulness from anesthesia-induced unconsciousness.

Authors:  Alexis T Baria; Maria V Centeno; Mariam E Ghantous; Pei C Chang; Daniele Procissi; A Vania Apkarian
Journal:  J Neurophysiol       Date:  2017-12-06       Impact factor: 2.714

3.  Breakdown in the temporal and spatial organization of spontaneous brain activity during general anesthesia.

Authors:  Jianfeng Zhang; Zirui Huang; Yali Chen; Jun Zhang; Diana Ghinda; Yuliya Nikolova; Jinsong Wu; Jianghui Xu; Wenjie Bai; Ying Mao; Zhong Yang; Niall Duncan; Pengmin Qin; Hao Wang; Bing Chen; Xuchu Weng; Georg Northoff
Journal:  Hum Brain Mapp       Date:  2018-01-28       Impact factor: 5.038

4.  An Integrated World Modeling Theory (IWMT) of Consciousness: Combining Integrated Information and Global Neuronal Workspace Theories With the Free Energy Principle and Active Inference Framework; Toward Solving the Hard Problem and Characterizing Agentic Causation.

Authors:  Adam Safron
Journal:  Front Artif Intell       Date:  2020-06-09

Review 5.  All roads lead to the motor cortex: psychomotor mechanisms and their biochemical modulation in psychiatric disorders.

Authors:  Paola Magioncalda; Matteo Martino; Georg Northoff; Dusan Hirjak; Robert C Wolf
Journal:  Mol Psychiatry       Date:  2020-06-17       Impact factor: 15.992

6.  Overcoming Rest-Task Divide-Abnormal Temporospatial Dynamics and Its Cognition in Schizophrenia.

Authors:  Georg Northoff; Javier Gomez-Pilar
Journal:  Schizophr Bull       Date:  2021-04-29       Impact factor: 9.306

7.  Anterior insula regulates brain network transitions that gate conscious access.

Authors:  Zirui Huang; Vijay Tarnal; Phillip E Vlisides; Ellen L Janke; Amy M McKinney; Paul Picton; George A Mashour; Anthony G Hudetz
Journal:  Cell Rep       Date:  2021-05-04       Impact factor: 9.423

8.  The neural correlates of the visual consciousness in schizophrenia: an fMRI study.

Authors:  S Lefebvre; E Very; R Jardri; M Horn; A Yrondi; C Delmaire; C Rascle; K Dujardin; P Thomas; D Pins
Journal:  Eur Arch Psychiatry Clin Neurosci       Date:  2020-08-19       Impact factor: 5.270

9.  Dynamic relationships between spontaneous and evoked electrophysiological activity.

Authors:  Soren Wainio-Theberge; Annemarie Wolff; Georg Northoff
Journal:  Commun Biol       Date:  2021-06-15

Review 10.  How Energy Supports Our Brain to Yield Consciousness: Insights From Neuroimaging Based on the Neuroenergetics Hypothesis.

Authors:  Yali Chen; Jun Zhang
Journal:  Front Syst Neurosci       Date:  2021-07-06
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