Literature DB >> 2876026

Control of Legionella in hospitals.

P H Edelstein.   

Abstract

Legionellas are present in water distribution systems and cooling towers of many hospitals. No firm data are available regarding the need for prophylactic disinfection of these contaminated systems. Disinfection of water systems and cooling towers is an accepted and effective means of ending nosocomial Legionnaires' disease, but it should be performed in conjunction with good epidemiological and microbiological studies to pinpoint environmental reservoirs and disseminators. Chlorination, pasteurization, or both, are the only means of disinfection found to be effective in disease outbreaks. Prospective surveillance of immuno compromised patients with pneumonia is probably the most effective means to determine if a hospital is a source of Legionnaires' disease and, therefore, requires further investigations and disinfection.

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Year:  1986        PMID: 2876026     DOI: 10.1016/0195-6701(86)90037-x

Source DB:  PubMed          Journal:  J Hosp Infect        ISSN: 0195-6701            Impact factor:   3.926


  13 in total

1.  Nosocomial Legionnaires' disease in England and Wales, 1980-92.

Authors:  C A Joseph; J M Watson; T G Harrison; C L Bartlett
Journal:  Epidemiol Infect       Date:  1994-04       Impact factor: 2.451

2.  Legionella pneumophila strain 130b possesses a unique combination of type IV secretion systems and novel Dot/Icm secretion system effector proteins.

Authors:  Gunnar N Schroeder; Nicola K Petty; Aurélie Mousnier; Clare R Harding; Adam J Vogrin; Bryan Wee; Norman K Fry; Timothy G Harrison; Hayley J Newton; Nicholas R Thomson; Scott A Beatson; Gordon Dougan; Elizabeth L Hartland; Gad Frankel
Journal:  J Bacteriol       Date:  2010-09-10       Impact factor: 3.490

3.  A field study of the survival of Legionella pneumophila in a hospital hot-water system.

Authors:  I D Farrell; J E Barker; E P Miles; J G Hutchison
Journal:  Epidemiol Infect       Date:  1990-06       Impact factor: 2.451

4.  Legionella pneumophila pathogenesis in the Galleria mellonella infection model.

Authors:  Clare R Harding; Gunnar N Schroeder; Stuart Reynolds; Artemis Kosta; James W Collins; Aurélie Mousnier; Gad Frankel
Journal:  Infect Immun       Date:  2012-05-29       Impact factor: 3.441

5.  Eliminating Legionella by inhibiting BCL-XL to induce macrophage apoptosis.

Authors:  Mary Speir; Kate E Lawlor; Stefan P Glaser; Gilu Abraham; Seong Chow; Adam Vogrin; Keith E Schulze; Ralf Schuelein; Lorraine A O'Reilly; Kylie Mason; Elizabeth L Hartland; Trevor Lithgow; Andreas Strasser; Guillaume Lessene; David C S Huang; James E Vince; Thomas Naderer
Journal:  Nat Microbiol       Date:  2016-02-24       Impact factor: 17.745

6.  Nosocomial legionellosis in three heart-lung transplant patients: case reports and environmental observations.

Authors:  J M Bangsborg; S Uldum; J S Jensen; B G Bruun
Journal:  Eur J Clin Microbiol Infect Dis       Date:  1995-02       Impact factor: 3.267

7.  Molecular fingerprinting of Legionella species by repetitive element PCR.

Authors:  P R Georghiou; A M Doggett; M A Kielhofner; J E Stout; D A Watson; J R Lupski; R J Hamill
Journal:  J Clin Microbiol       Date:  1994-12       Impact factor: 5.948

8.  Fatal nosocomial Legionnaires' disease: relevance of contamination of hospital water supply by temperature-dependent buoyancy-driven flow from spur pipes.

Authors:  W J Patterson; D V Seal; E Curran; T M Sinclair; J C McLuckie
Journal:  Epidemiol Infect       Date:  1994-06       Impact factor: 2.451

9.  Legionella pneumophila Effector LpdA Is a Palmitoylated Phospholipase D Virulence Factor.

Authors:  Gunnar N Schroeder; Philipp Aurass; Clare V Oates; Edward W Tate; Elizabeth L Hartland; Antje Flieger; Gad Frankel
Journal:  Infect Immun       Date:  2015-07-27       Impact factor: 3.441

10.  The Dot/Icm effector SdhA is necessary for virulence of Legionella pneumophila in Galleria mellonella and A/J mice.

Authors:  Clare R Harding; Charlotte A Stoneham; Ralf Schuelein; Hayley Newton; Clare V Oates; Elizabeth L Hartland; Gunnar N Schroeder; Gad Frankel
Journal:  Infect Immun       Date:  2013-05-06       Impact factor: 3.441

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