Literature DB >> 28759318

The Public Health Burden of Lymphatic Malformations in Children: National Estimates in the United States, 2000-2009.

Jeffrey Cheng1, Beiyu Liu2, Alfredo E Farjat2, Jonathan Routh3.   

Abstract

OBJECTIVE: Describe inpatient resource utilization trends in children with lymphatic malformations using a national database. DATA SOURCE: Kids' inpatient database, years 2000-2009.
METHODS: Subjects included children 18 years and under with International Classification of Diseases (ICD), 9th revision code: 228.1-lymphangioma, any site. Data elements were extracted and used to calculate related inpatient costs and trended over time.
RESULTS: No significant increase in admission rates was noted over time, p = 0.5128. Average total charges per admission were $30,995. There is a clear and increasing trend of total charges per admission; even when adjusted for inflation, this has increased disproportionately. In 2009, the mortality rate increased to 2.58%, which was significantly higher than in previous years, p = 0.0346. In multivariate analysis for mortality, the only factor that was noted to be significant was between survey years 2000 and 2009. The odds ratio (OR) for mortality was 2.97, 95% CI: [1.423-6.202], which indicated that there was an almost three times higher likelihood of mortality in 2009 than in 2000.
CONCLUSIONS: Admission rates appear to remain stable for pediatric inpatients with lymphatic malformations but resource utilization related to charges has been increasing from 2000 to 2009. Controlling for inflation does not explain our observed trend in total charge increases. Previously, surgical resection was the most commonly performed procedure, and now the trend has shifted away from operative intervention. Mortality rates, while low, experienced a rise in 2009. Further investigation may be warranted.

Entities:  

Keywords:  HCUP; KID database; costs; lymphangioma; lymphatic malformation; resource utilization; sclerotherapy

Mesh:

Year:  2017        PMID: 28759318      PMCID: PMC5647489          DOI: 10.1089/lrb.2017.0009

Source DB:  PubMed          Journal:  Lymphat Res Biol        ISSN: 1539-6851            Impact factor:   2.589


  13 in total

1.  Pediatric admissions and procedures for lymphatic malformations in the United States: 1997 and 2000.

Authors:  Wayne J Harsha; Jonathan A Perkins; Charlotte W Lewis; Scott C Manning
Journal:  Lymphat Res Biol       Date:  2005       Impact factor: 2.589

Review 2.  Current treatment paradigms in the management of lymphatic malformations.

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Review 3.  Multidisciplinary treatment of extremity arteriovenous malformations.

Authors:  Jovan N Markovic; Cynthia E K Shortell
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Review 4.  Treatment guidelines of lymphatic malformations of the head and neck.

Authors:  Qin Zhou; Jia Wei Zheng; Hua Ming Mai; Quan Feng Luo; Xin Dong Fan; Li Xin Su; Yan An Wang; Zhong Ping Qin
Journal:  Oral Oncol       Date:  2011-09-08       Impact factor: 5.337

5.  Lymphangiomas in children: percutaneous sclerotherapy with an alcoholic solution of zein.

Authors:  J Dubois; L Garel; A Abela; L Laberge; S Yazbeck
Journal:  Radiology       Date:  1997-09       Impact factor: 11.105

Review 6.  Vascular Anomalies in Pediatrics.

Authors:  Lisa S Foley; Ann M Kulungowski
Journal:  Adv Pediatr       Date:  2015-08

7.  Facial nerve mapping and monitoring in lymphatic malformation surgery.

Authors:  Jospeh Chiara; Greg Kinney; Jefferson Slimp; Gi Soo Lee; Sepehr Oliaei; Jonathan A Perkins
Journal:  Int J Pediatr Otorhinolaryngol       Date:  2009-07-09       Impact factor: 1.675

8.  Primary surgery vs primary sclerotherapy for head and neck lymphatic malformations.

Authors:  Karthik Balakrishnan; Maithilee D Menezes; Brian S Chen; Anthony E Magit; Jonathan A Perkins
Journal:  JAMA Otolaryngol Head Neck Surg       Date:  2014-01       Impact factor: 6.223

9.  Vascular Anomalies: The Epidemiological Profile at Srinagarind Hospital.

Authors:  Leelawadee Techasatian; Patchareeporn Tanming; Sunee Panombualert; Rattapon Uppala; Charoon Jetsrisuparb
Journal:  J Med Assoc Thai       Date:  2015-08

10.  Clinical outcomes in lymphocytopenic lymphatic malformation patients.

Authors:  Jonathan A Perkins; Richard M Tempero; Mark C Hannibal; Scott C Manning
Journal:  Lymphat Res Biol       Date:  2007       Impact factor: 2.589

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  1 in total

1.  30-Day outcomes analysis of NSQIP-pediatric for surgical management of head and neck lymphatic malformations in children.

Authors:  Jeffrey Cheng; Beiyu Liu; Hui-Jie Lee
Journal:  Int J Pediatr Otorhinolaryngol       Date:  2018-12-07       Impact factor: 1.675

  1 in total

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