Literature DB >> 28757631

Cancer: RNA-based approaches target KRAS.

Sarah Crunkhorn.   

Abstract

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Year:  2017        PMID： 28757631     DOI： 10.1038/nrd.2017.137

Source DB:  PubMed          Journal:  Nat Rev Drug Discov        ISSN： 1474-1776            Impact factor:   84.694


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  2 in total

1.  Targeting KRAS-dependent tumors with AZD4785, a high-affinity therapeutic antisense oligonucleotide inhibitor of KRAS.

Authors:  Sarah J Ross; Alexey S Revenko; Lyndsey L Hanson; Rebecca Ellston; Anna Staniszewska; Nicky Whalley; Sanjay K Pandey; Mitchell Revill; Claire Rooney; Linda K Buckett; Stephanie K Klein; Kevin Hudson; Brett P Monia; Michael Zinda; David C Blakey; Paul D Lyne; A Robert Macleod
Journal:  Sci Transl Med       Date:  2017-06-14       Impact factor: 17.956

2.  Exosomes facilitate therapeutic targeting of oncogenic KRAS in pancreatic cancer.

Authors:  Sushrut Kamerkar; Valerie S LeBleu; Hikaru Sugimoto; Sujuan Yang; Carolina F Ruivo; Sonia A Melo; J Jack Lee; Raghu Kalluri
Journal:  Nature       Date:  2017-06-07       Impact factor: 49.962
  2 in total

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