| Literature DB >> 28757114 |
Julie Carrier1, Kazue Semba2, Samuel Deurveilher3, Lauren Drogos4, Jessica Cyr-Cronier5, Catherine Lord5, Zoran Sekerovick5.
Abstract
Age-related changes in sleep and circadian regulation occur as early as the middle years of life. Research also suggests that sleep and circadian rhythms are regulated differently between women and men. However, does sleep and circadian rhythms regulation age similarly in men and women? In this review, we present the mechanisms underlying age-related differences in sleep and the current state of knowledge on how they interact with sex. We also address how testosterone, estrogens, and progesterone fluctuations across adulthood interact with sleep and circadian regulation. Finally, we will propose research avenues to unravel the mechanisms underlying sex differences in age-related effects on sleep.Entities:
Keywords: Aging; Andropause; Circadian rhythms; Estrogens; Menopause; Sex differences; Sleep; Testosterone
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Year: 2017 PMID： 28757114 DOI： 10.1016/j.yfrne.2017.07.004
Source DB: PubMed Journal: Front Neuroendocrinol ISSN： 0091-3022 Impact factor: 8.606