Literature DB >> 28756762

Update on the prevention of death from ruptured abdominal aortic aneurysm.

Jo Jacomelli1, Lisa Summers1, Anne Stevenson1, Tim Lees2, Jonothan J Earnshaw3.   

Abstract

Objectives To monitor the early effect of a national population screening programme for abdominal aortic aneurysm in 65-year-old men. Setting The study used national statistics for death rates from abdominal aortic aneurysm (Office of National Statistics) and hospital admission data in England (Hospital Episode Statistics). Methods Information concerning deaths from abdominal aortic aneurysm (ruptured and non-ruptured) (1999-2014) and hospital admissions for ruptured abdominal aortic aneurysm (2000-2015) was examined. Results The absolute number of deaths from abdominal aortic aneurysm in men and women aged 65 and over has decreased by around 30% from 2001 to 2014, but as the population has increased, the relative reduction was 45.6% and 40.0%, respectively. Some 65% of all abdominal aortic aneurysm deaths are in men aged over 65; women aged 65 and over account for around 31%. Deaths from ruptured abdominal aortic aneurysm in men aged 60-74 (the screened group) appear to be declining at the same rate as in men aged 75 and over. The relative decline in admissions to hospital with ruptured abdominal aortic aneurysm may be greater in men and women aged 60-74 (which contains the screened group of men), than those older, giving the first possible evidence that abdominal aortic aneurysm screening is having an effect. Conclusion The death rate from abdominal aortic aneurysm is declining rapidly in England. There is the first evidence that screening may be contributing to this reduction.

Entities:  

Keywords:  Aortic aneurysm; aortic aneurysm screening; ruptured aortic aneurysm

Mesh:

Year:  2016        PMID: 28756762     DOI: 10.1177/0969141316667409

Source DB:  PubMed          Journal:  J Med Screen        ISSN: 0969-1413            Impact factor:   2.136


  6 in total

1.  Safety of Men With Small and Medium Abdominal Aortic Aneurysms Under Surveillance in the NAAASP.

Authors:  Clare Oliver-Williams; Michael J Sweeting; Jo Jacomelli; Lisa Summers; Anne Stevenson; Tim Lees; Jonothan J Earnshaw
Journal:  Circulation       Date:  2019-03-12       Impact factor: 29.690

2.  Retrospective review of abdominal aortic aneurysm deaths in New Zealand: what proportion of deaths is potentially preventable by a screening programme in the contemporary setting?

Authors:  Wing Cheuk Chan; Dean Papaconstantinou; Doone Winnard; Gary Jackson
Journal:  BMJ Open       Date:  2019-07-30       Impact factor: 2.692

Review 3.  Matrix Metalloproteinase in Abdominal Aortic Aneurysm and Aortic Dissection.

Authors:  Eithne M Maguire; Stuart W A Pearce; Rui Xiao; Aung Y Oo; Qingzhong Xiao
Journal:  Pharmaceuticals (Basel)       Date:  2019-08-06

4.  Metformin represses the pathophysiology of AAA by suppressing the activation of PI3K/AKT/mTOR/autophagy pathway in ApoE-/- mice.

Authors:  Zhu Wang; Jingjing Guo; Xinqiang Han; Ming Xue; Wenming Wang; Lei Mi; Yuguo Sheng; Chao Ma; Jian Wu; Xuejun Wu
Journal:  Cell Biosci       Date:  2019-08-27       Impact factor: 7.133

Review 5.  Pathogenic mechanisms and the potential of drug therapies for aortic aneurysm.

Authors:  Bo Liu; David J Granville; Jonathan Golledge; Zamaneh Kassiri
Journal:  Am J Physiol Heart Circ Physiol       Date:  2020-02-21       Impact factor: 4.733

6.  Modelling the impact of changes to abdominal aortic aneurysm screening and treatment services in England during the COVID-19 pandemic.

Authors:  Lois G Kim; Michael J Sweeting; Morag Armer; Jo Jacomelli; Akhtar Nasim; Seamus C Harrison
Journal:  PLoS One       Date:  2021-06-15       Impact factor: 3.240

  6 in total

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