Literature DB >> 28756402

Comparison of a structured home-based rehabilitation programme with conventional supervised pulmonary rehabilitation: a randomised non-inferiority trial.

Elizabeth J Horton1, Katy E Mitchell2, Vicki Johnson-Warrington2, Lindsay D Apps2, Louise Sewell2, Mike Morgan2, Rod S Taylor3, Sally J Singh2,4.   

Abstract

BACKGROUND: Standardised home-based pulmonary rehabilitation (PR) programmes offer an alternative model to centre-based supervised PR for which uptake is currently poor. We determined if a structured home-based unsupervised PR programme was non-inferior to supervised centre-based PR for participants with COPD.
METHODS: A total of 287 participants with COPD who were referred to PR (187 male, mean (SD) age 68 (8.86) years, FEV1% predicted 48.34 (17.92)) were recruited. They were randomised to either centre-based PR or a structured unsupervised home-based PR programme including a hospital visit with a healthcare professional trained in motivational interviewing, a self-management manual and two telephone calls. Fifty-eight (20%) withdrew from the centre-based group and 51 (18%) from the home group. The primary outcome was dyspnoea domain in the chronic respiratory disease questionnaire (Chronic Respiratory Questionnaire Self-Report; CRQ-SR) at 7 weeks. Measures were taken blinded. We undertook a modified intention-to-treat (mITT) complete case analysis, comparing groups according to original random allocation and with complete data at follow-up. The non-inferiority margin was 0.5 units.
RESULTS: There was evidence of significant gains in CRQ-dyspnoea at 7 weeks in both home and centre-based groups. There was inconclusive evidence that home-based PR was non-inferior to PR in dyspnoea (mean group difference, mITT: -0.24, 95% CI -0.61 to 0.12, p=0.18), favouring the centre group at 7 weeks.
CONCLUSIONS: The standardised home-based programme provides benefits in dyspnoea. Further evidence is needed to definitively determine if the health benefits of the standardised home-based programme are non-inferior or equivalent to supervised centre-based rehabilitation. TRIAL REGISTRATION NUMBER: ISRCTN81189044. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

Entities:  

Keywords:  exercise; pulmonary rehabilitation

Mesh：

Year:  2017        PMID： 28756402     DOI： 10.1136/thoraxjnl-2016-208506

Source DB:  PubMed          Journal:  Thorax        ISSN： 0040-6376            Impact factor:   9.139


  36 in total

Review 1.  Pulmonary rehabilitation in patients with an acute exacerbation of chronic obstructive pulmonary disease.

Authors:  Sarah E Jones; Ruth E Barker; Claire M Nolan; Suhani Patel; Matthew Maddocks; William D C Man
Journal:  J Thorac Dis       Date:  2018-05       Impact factor: 2.895

2.  Comparison of Compliance Rates and Treatment Efficiency in Home-Based with Hospital-Based Pulmonary Rehabilitation in COPD.

Authors:  Esra Pehlivan; Esra Yazar; Arif Balcı; Lütfiye Kılıç
Journal:  Turk Thorac J       Date:  2019-07-01

Review 3.  Organization of Rehabilitation Services in Randomized Controlled Trials: Which Factors Influence Functional Outcome? A Systematic Review.

Authors:  Cecilie Røe; Erik Bautz-Holter; Nada Andelic; Helene Lundgaard Søberg; Boya Nugraha; Christoph Gutenbrunner; Andrea Boekel; Marit Kirkevold; Grace Engen; Juan Lu
Journal:  Arch Rehabil Res Clin Transl       Date:  2022-04-13

4.  Video Telehealth Pulmonary Rehabilitation for Chronic Obstructive Pulmonary Disease Is Associated with Clinical Improvement Similar to Center-based Pulmonary Rehabilitation.

Authors:  Surya P Bhatt; Daniel Baugh; Jason Hitchcock; Young-Il Kim; Gary Cutter; Inmaculada Aban; Mark T Dransfield
Journal:  Ann Am Thorac Soc       Date:  2022-02

5.  Inter-Day Test-Retest Reproducibility of the CAT, CCQ, HADS and EQ-5D-3L in Patients with Severe and Very Severe COPD.

Authors:  Henrik Hansen; Nina Beyer; Anne Frølich; Nina Godtfredsen; Theresa Bieler
Journal:  Patient Relat Outcome Meas       Date:  2021-06-01

6.  Individualized, low-cost and accessible pulmonary rehabilitation program based on functional clinical tests for individuals with COPD-a study protocol of a randomized controlled trial.

Authors:  Marcela Maria Carvalho da Silva; Juliano Ferreira Arcuri; Valéria Amorim Pires Di Lorenzo
Journal:  Trials       Date:  2021-05-26       Impact factor: 2.279

7.  Effects of a Home-Based Pulmonary Rehabilitation Program in Patients with Chronic Obstructive Pulmonary Disease in GOLD B Group: A Pilot Study.

Authors:  Rui Vilarinho; Lúcia Serra; Ricardo Coxo; João Carvalho; Cátia Esteves; António Mesquita Montes; Cátia Caneiras
Journal:  Healthcare (Basel)       Date:  2021-05-04

8.  Web-Based Self-management Program (SPACE for COPD) for Individuals Hospitalized With an Acute Exacerbation of Chronic Obstructive Pulmonary Disease: Nonrandomized Feasibility Trial of Acceptability.

Authors:  Linzy Houchen-Wolloff; Mark Orme; Amy Barradell; Lisa Clinch; Emma Chaplin; Nikki Gardiner; Sally J Singh
Journal:  JMIR Mhealth Uhealth       Date:  2021-06-11       Impact factor: 4.773

9.  Interventions for promoting physical activity in people with chronic obstructive pulmonary disease (COPD).

Authors:  Angela T Burge; Narelle S Cox; Michael J Abramson; Anne E Holland
Journal:  Cochrane Database Syst Rev       Date:  2020-04-16

10.  Effectiveness of Rehabilitation Nursing versus Usual Therapist-Led Treatment in Patients with Acute Ischemic Stroke: A Randomized Non-Inferiority Trial.

Authors:  Jianmiao Wang; Yuping Zhang; Yuanyuan Chen; Mei Li; Hongyan Yang; Jinhua Chen; Qiaomin Tang; Jingfen Jin
Journal:  Clin Interv Aging       Date:  2021-06-21       Impact factor: 4.458
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