Literature DB >> 287547

Prognostic significance of alkaline phosphatase measurements in patients with osteogenic sarcoma receiving chemotherapy.

W P Thorpe, J J Reilly, S A Rosenberg.   

Abstract

During the period January 1975 to August 1977, alkaline phosphatase levels in 30 patients with osteogenic sarcoma were closely followed in an attempt to determine if these measurements had clinical value in predicting the course of patients with this disease. Of 17 patients with elevated preoperative alkaline phosphatase levels, 12 recurred. Of 13 patients with normal preoperative alkaline phosphatase levels, only 4 recurred (p less than .05). Thus, alkaline phosphatase levels that were elevated preoperatively were correlated with poor prognosis. A similar correlation between postoperative alkaline phosphatase levels and prognosis could not be made.

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Year:  1979        PMID: 287547     DOI: 10.1002/1097-0142(197906)43:6<2178::aid-cncr2820430603>3.0.co;2-9

Source DB:  PubMed          Journal:  Cancer        ISSN: 0008-543X            Impact factor:   6.860


  6 in total

1.  Induced pluripotency and oncogenic transformation are related processes.

Authors:  John W Riggs; Bonnie L Barrilleaux; Natasha Varlakhanova; Kelly M Bush; Vanessa Chan; Paul S Knoepfler
Journal:  Stem Cells Dev       Date:  2012-10-26       Impact factor: 3.272

Review 2.  The multidisciplinary management of osteosarcoma.

Authors:  Noah Federman; Nicholas Bernthal; Fritz C Eilber; William D Tap
Journal:  Curr Treat Options Oncol       Date:  2009-02-24

3.  Primary osteosarcoma in patients older than 40 years of age.

Authors:  Dae Geun Jeon; Soo Yong Lee; Wan Hyung Cho; Won Seok Song; Jong Hoon Park
Journal:  J Korean Med Sci       Date:  2006-08       Impact factor: 2.153

Review 4.  A review of clinical and molecular prognostic factors in osteosarcoma.

Authors:  Jonathan C M Clark; Crispin R Dass; Peter F M Choong
Journal:  J Cancer Res Clin Oncol       Date:  2007-10-27       Impact factor: 4.553

5.  Secondary osteosarcoma arising after treatment for childhood hematologic malignancies.

Authors:  Atsushi Okada; Masahito Hatori; Masami Hosaka; Munenori Watanuki; Eiji Itoi
Journal:  Ups J Med Sci       Date:  2009       Impact factor: 2.384

6.  High serum alkaline phosphatase cooperating with MMP-9 predicts metastasis and poor prognosis in patients with primary osteosarcoma in Southern China.

Authors:  Ju Han; Bicheng Yong; Canqiao Luo; Pingxian Tan; Tingsheng Peng; Jingnan Shen
Journal:  World J Surg Oncol       Date:  2012-02-15       Impact factor: 2.754

  6 in total

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