Literature DB >> 28753421

Drugs, Bugs, and Cancer: Fusobacterium nucleatum Promotes Chemoresistance in Colorectal Cancer.

Azucena Ramos1, Michael T Hemann2.   

Abstract

The tumor microenvironment has recently been shown to play decisive roles in chemotherapeutic response. In this issue of Cell, Yu et al. add to these findings by identifying the bacterium Fusobacterium nucleatum as a previously unrecognized chemoresistance mediator in colorectal cancer, thereby establishing the microbiota as a potential therapeutic target.
Copyright © 2017. Published by Elsevier Inc.

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Year:  2017        PMID: 28753421     DOI: 10.1016/j.cell.2017.07.018

Source DB:  PubMed          Journal:  Cell        ISSN: 0092-8674            Impact factor:   41.582


  18 in total

Review 1.  The role of gut microbiota in the development of colorectal cancer: a review.

Authors:  Navami Koyande; Madhusree Gangopadhyay; Shashidhar Thatikonda; Aravind Kumar Rengan
Journal:  Int J Colorectal Dis       Date:  2022-06-15       Impact factor: 2.796

2.  Mice with dysfunctional TGF-β signaling develop altered intestinal microbiome and colorectal cancer resistant to 5FU.

Authors:  Zhanhuai Wang; Lindsay M Hopson; Stephanie S Singleton; Xiaochun Yang; Wilma Jogunoori; Raja Mazumder; Vincent Obias; Paul Lin; Bao-Ngoc Nguyen; Michael Yao; Larry Miller; Jon White; Shuyun Rao; Lopa Mishra
Journal:  Biochim Biophys Acta Mol Basis Dis       Date:  2021-05-31       Impact factor: 5.187

3.  Analysis of chronic inflammatory lesions of the colon for BMMF Rep antigen expression and CD68 macrophage interactions.

Authors:  Timo Bund; Ekaterina Nikitina; Deblina Chakraborty; Claudia Ernst; Karin Gunst; Boyana Boneva; Claudia Tessmer; Nadine Volk; Alexander Brobeil; Achim Weber; Mathias Heikenwalder; Harald Zur Hausen; Ethel-Michele de Villiers
Journal:  Proc Natl Acad Sci U S A       Date:  2021-03-23       Impact factor: 12.779

Review 4.  Organoids Provide an Important Window on Inflammation in Cancer.

Authors:  Kristi Baker
Journal:  Cancers (Basel)       Date:  2018-05-21       Impact factor: 6.639

5.  Microbial Biogeography Along the Gastrointestinal Tract of a Red Panda.

Authors:  Yan Zeng; Dong Zeng; Yi Zhou; Lili Niu; Jiabo Deng; Yang Li; Yang Pu; Yicen Lin; Shuai Xu; Qian Liu; Lvchen Xiong; Mengjia Zhou; Kangcheng Pan; Bo Jing; Xueqin Ni
Journal:  Front Microbiol       Date:  2018-07-05       Impact factor: 5.640

Review 6.  Harnessing the innate immune system and local immunological microenvironment to treat colorectal cancer.

Authors:  Jakob Nikolas Kather; Niels Halama
Journal:  Br J Cancer       Date:  2019-04-02       Impact factor: 7.640

Review 7.  Fusobacterium nucleatum-positive colorectal cancer.

Authors:  Zhenhua Yang; Guang Ji
Journal:  Oncol Lett       Date:  2019-06-04       Impact factor: 2.967

Review 8.  Pathophysiological Characteristics Linking Type 2 Diabetes Mellitus and Colorectal Neoplasia.

Authors:  T Grega; G Vojtechova; M Gregova; M Zavoral; S Suchanek
Journal:  Physiol Res       Date:  2021-06-01       Impact factor: 1.881

9.  Preliminary Comparison of Oral and Intestinal Human Microbiota in Patients with Colorectal Cancer: A Pilot Study.

Authors:  Edda Russo; Giovanni Bacci; Carolina Chiellini; Camilla Fagorzi; Elena Niccolai; Antonio Taddei; Federica Ricci; Maria N Ringressi; Rossella Borrelli; Filippo Melli; Manouela Miloeva; Paolo Bechi; Alessio Mengoni; Renato Fani; Amedeo Amedei
Journal:  Front Microbiol       Date:  2018-01-12       Impact factor: 5.640

10.  miR-375-3p suppresses tumorigenesis and partially reverses chemoresistance by targeting YAP1 and SP1 in colorectal cancer cells.

Authors:  Xueni Xu; Xiaoxiang Chen; Mu Xu; Xiangxiang Liu; Bei Pan; Jian Qin; Tao Xu; Kaixuan Zeng; Yuqin Pan; Bangshun He; Huiling Sun; Li Sun; Shukui Wang
Journal:  Aging (Albany NY)       Date:  2019-09-22       Impact factor: 5.682

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