Literature DB >> 2875024

Effect of parathyroid hormone on plasma renin activity in humans.

P D Broulik, K Horký, V Pacovský.   

Abstract

The effect of PTH infusion on PRA was evaluated in 22 normotensive subjects. Intravenous infusion of PTH produced an increase in PRA in studied subjects. This increase in PRA was dose dependent from 1.505 +/- 0.226 to 2.500 +/- 0.346 nmol/l/hour after administration of 100 units of PTH and from 1.648 +/- 0.189 to 4.294 +/- 0.614 nmol/l/hour after 200 units of PTH and was markedly decreased by a beta blocking drug from 1.660 +/- 0.259 to 2.498 +/- 0.485 nmol/l/hour. These responses were observed without any significant changes in plasma calcium and blood pressure. From our results we can conclude that PTH increases PRA in normotensive controls. This effect is partly blocked by beta adrenergic blockers.

Entities:  

Mesh：

Substances：

Year:  1986        PMID： 2875024     DOI： 10.1055/s-2007-1012353

Source DB:  PubMed          Journal:  Horm Metab Res        ISSN： 0018-5043            Impact factor:   2.936


  7 in total

Review 1.  Vitamin D: Metabolism, Molecular Mechanism of Action, and Pleiotropic Effects.

Authors:  Sylvia Christakos; Puneet Dhawan; Annemieke Verstuyf; Lieve Verlinden; Geert Carmeliet
Journal:  Physiol Rev       Date:  2016-01       Impact factor: 37.312

2.  1,25-Dihydroxyvitamin D(3) is a negative endocrine regulator of the renin-angiotensin system.

Authors:  Yan Chun Li; Juan Kong; Minjie Wei; Zhou-Feng Chen; Shu Q Liu; Li-Ping Cao
Journal:  J Clin Invest       Date:  2002-07       Impact factor: 14.808

3.  Prevalence of calcified carotid artery atheromas on panoramic images of individuals with primary hyperparathyroidism.

Authors:  A H Friedlander; N Aghazadehsanai; T I Chang; N Harada; N R Garrett
Journal:  Dentomaxillofac Radiol       Date:  2013-06-17       Impact factor: 2.419

4.  Improvement of hypertension after parathyroidectomy of patients suffering from primary hyperparathyroidism.

Authors:  P D Broulik; A Brouliková; S Adámek; P Libanský; J Tvrdoň; K Broulikova; J Kubinyi
Journal:  Int J Endocrinol       Date:  2011-02-20       Impact factor: 3.257

Review 5.  Links between Vitamin D Deficiency and Cardiovascular Diseases.

Authors:  Ioana Mozos; Otilia Marginean
Journal:  Biomed Res Int       Date:  2015-04-27       Impact factor: 3.411

6.  Parathyroidectomy Ameliorates Glucose and Blood Pressure Control in a Patient with Primary Hyperparathyroidism, Type 2 Diabetes, and Hypertension.

Authors:  Alok Kumar; Sunita Singh
Journal:  Clin Med Insights Endocrinol Diabetes       Date:  2015-09-02

Review 7.  The Interplay Between the Renin-Angiotensin-Aldosterone System and Parathyroid Hormone.

Authors:  Ming-Hui Zheng; Fu-Xing-Zi Li; Feng Xu; Xiao Lin; Yi Wang; Qiu-Shuang Xu; Bei Guo; Ling-Qing Yuan
Journal:  Front Endocrinol (Lausanne)       Date:  2020-08-20       Impact factor: 5.555
  7 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.