Importance: Hearing loss (HL), a major cause of disability globally, negatively affects both personal and professional life. Objective: To describe the prevalence of sensorineural hearing loss (SNHL) among a population-based cohort of 9- to 11-year-old children, and to examine potential associations between purported risk factors and SNHL in early childhood. Design, Setting, and Participants: The study was among the general, nonclinical, pediatric community within the city of Rotterdam, the Netherlands, and was conducted between 2012 and 2015 as a cross-sectional assessment within the Generation R Study, a population-based longitudinal cohort study from fetal life until adulthood. Participants are children of included pregnant women in the Generation R Study with an expected delivery date between April 2002 and January 2006. They form a prenatally recruited birth cohort. Main Outcomes and Measures: Pure-tone air-conduction hearing thresholds were obtained at 0.5, 1, 2, 3, 4, 6, and 8 kHz, and tympanometry was performed in both ears. Demographic factors and parent-reported questionnaire data, including history of otitis media, were also measured. Results: A total of 5368 participants with a mean age of 9 years 9 months (interquartile range, 9 years 7 months-9 years 11 months) completed audiometry and were included in the analyses. A total of 2720 were girls (50.7%), and 3627 (67.6%) were white. Most of the participants (4426 children [82.5%]) showed normal hearing thresholds 15 dB HL or less in both ears. Within the cohort, 418 children (7.8%) were estimated to have SNHL (≥16 dB HL at low-frequency pure-tone average; average at 0.5, 1, and 2 kHz or high-frequency pure-tone average; average at 3, 4, and 6 kHz in combination with a type A tympanogram) in at least 1 ear, most often at higher frequencies. In multivariable analyses, a history of recurrent acute otitis media and lower maternal education were associated with the estimated SNHL at ages 9 to 11 years (odds ratio, 2.0 [95% CI. 1.5-2.8] and 1.4 [95% CI, 1.1-1.7], respectively). Conclusions and Relevance: Within this cohort study in the Netherlands, 7.8% of the children ages 9 to 11 years had low-frequency or high-frequency HL of at least 16 dB HL in 1 or both ears. A history of recurrent acute otitis media and lower maternal education seem to be independent risk factors for presumed SNHL in early childhood.
Importance: Hearing loss (HL), a major cause of disability globally, negatively affects both personal and professional life. Objective: To describe the prevalence of sensorineural hearing loss (SNHL) among a population-based cohort of 9- to 11-year-old children, and to examine potential associations between purported risk factors and SNHL in early childhood. Design, Setting, and Participants: The study was among the general, nonclinical, pediatric community within the city of Rotterdam, the Netherlands, and was conducted between 2012 and 2015 as a cross-sectional assessment within the Generation R Study, a population-based longitudinal cohort study from fetal life until adulthood. Participants are children of included pregnant women in the Generation R Study with an expected delivery date between April 2002 and January 2006. They form a prenatally recruited birth cohort. Main Outcomes and Measures: Pure-tone air-conduction hearing thresholds were obtained at 0.5, 1, 2, 3, 4, 6, and 8 kHz, and tympanometry was performed in both ears. Demographic factors and parent-reported questionnaire data, including history of otitis media, were also measured. Results: A total of 5368 participants with a mean age of 9 years 9 months (interquartile range, 9 years 7 months-9 years 11 months) completed audiometry and were included in the analyses. A total of 2720 were girls (50.7%), and 3627 (67.6%) were white. Most of the participants (4426 children [82.5%]) showed normal hearing thresholds 15 dB HL or less in both ears. Within the cohort, 418 children (7.8%) were estimated to have SNHL (≥16 dB HL at low-frequency pure-tone average; average at 0.5, 1, and 2 kHz or high-frequency pure-tone average; average at 3, 4, and 6 kHz in combination with a type A tympanogram) in at least 1 ear, most often at higher frequencies. In multivariable analyses, a history of recurrent acute otitis media and lower maternal education were associated with the estimated SNHL at ages 9 to 11 years (odds ratio, 2.0 [95% CI. 1.5-2.8] and 1.4 [95% CI, 1.1-1.7], respectively). Conclusions and Relevance: Within this cohort study in the Netherlands, 7.8% of the children ages 9 to 11 years had low-frequency or high-frequency HL of at least 16 dB HL in 1 or both ears. A history of recurrent acute otitis media and lower maternal education seem to be independent risk factors for presumed SNHL in early childhood.
Authors: Marjolein N Kooijman; Claudia J Kruithof; Cornelia M van Duijn; Liesbeth Duijts; Oscar H Franco; Marinus H van IJzendoorn; Johan C de Jongste; Caroline C W Klaver; Aad van der Lugt; Johan P Mackenbach; Henriëtte A Moll; Robin P Peeters; Hein Raat; Edmond H H M Rings; Fernando Rivadeneira; Marc P van der Schroeff; Eric A P Steegers; Henning Tiemeier; André G Uitterlinden; Frank C Verhulst; Eppo Wolvius; Janine F Felix; Vincent W V Jaddoe Journal: Eur J Epidemiol Date: 2017-01-09 Impact factor: 8.082
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Authors: Carlijn M P le Clercq; André Goedegebure; Vincent W V Jaddoe; Hein Raat; Robert J Baatenburg de Jong; Marc P van der Schroeff Journal: JAMA Otolaryngol Head Neck Surg Date: 2018-08-01 Impact factor: 6.223
Authors: Julia Smith; Jing Wang; Anneke C Grobler; Katherine Lange; Susan A Clifford; Melissa Wake Journal: BMJ Open Date: 2019-07-04 Impact factor: 2.692
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Authors: Daniel N Frank; Jose Pedrito M Magno; Karen Joyce S Velasco; Tori C Bootpetch; Jacob Ephraim D Salud; Kevin Jer V David; Aaron L Miller; Eljohn C Yee; Heather P Dulnuan; Richard B Pyles; Jan Alexeis C Lacuata; Jeric L Arbizo; Jennifer M Kofonow; Beatrice Guce; Kevin Michael D Mendoza; Charles E Robertson; Gabriel Martin S Ilustre; Alessandra Nadine E Chiong; Shi-Long Lu; Erik A Tongol; Nicole D Sacayan; Talitha Karisse L Yarza; Charlotte M Chiong; Regie Lyn P Santos-Cortez Journal: Front Cell Infect Microbiol Date: 2022-04-19 Impact factor: 6.073
Authors: Elzbieta Gos; Piotr Henryk Skarzynski; Natalia Czajka; Monika Matusiak; Wojciech Kazmierczak; Joanna Janiak-Kiszka; Katarzyna Beata Cywka; Henryk Skarzynski Journal: J Int Adv Otol Date: 2022-03 Impact factor: 1.316