Literature DB >> 28748665

CD4+ Cell infiltration into subcutaneous adipose tissue is not indicative of productively infected cells during acute SHIV infection.

Denise C Hsu1,2,3, Matthew D Wegner1, Piyanate Sunyakumthorn1, Decha Silsorn1, Sujitra Tayamun1, Dutsadee Inthawong1, Yanin Kuncharin1, Rawiwan Im-Erbsin1, Christine Ege1, Robert J O'Connell1,2, Nelson L Michael2, Lishomwa C Ndhlovu4, Sandhya Vasan1,2,3.   

Abstract

Limited longitudinal data exist on the effect of HIV on adipose tissue (AT). We found an increase in CD4+ cells and detectable SHIV-RNA in AT during acute SHIV infection. SHIV-RNA+ cells were rare, suggesting that AT is unlikely to be a major source of productively infected cells in SHIV infection.
© 2017 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

Entities:  

Keywords:  zzm321990HIVzzm321990; zzm321990RNAzzm321990; CD4; fat; inflammation

Mesh：

Year:  2017        PMID： 28748665     DOI： 10.1111/jmp.12298

Source DB:  PubMed          Journal:  J Med Primatol        ISSN： 0047-2565            Impact factor:   0.667


  6 in total

Review 1.  HIV Persistence in Adipose Tissue Reservoirs.

Authors:  Jacob Couturier; Dorothy E Lewis
Journal:  Curr HIV/AIDS Rep       Date:  2018-02       Impact factor: 5.071

2.  Association of Male Sex and Obesity With Residual Plasma Human Immunodeficiency Virus 1 Viremia in Persons on Long-Term Antiretroviral Therapy.

Authors:  Joshua C Cyktor; Ronald J Bosch; Hanna Mar; Bernard J Macatangay; Ann C Collier; Evelyn Hogg; Catherine Godfrey; Joseph J Eron; Deborah K McMahon; John W Mellors; Rajesh T Gandhi
Journal:  J Infect Dis       Date:  2021-02-13       Impact factor: 7.759

Review 3.  Adipose Tissue T Cells in HIV/SIV Infection.

Authors:  Celestine N Wanjalla; Wyatt J McDonnell; John R Koethe
Journal:  Front Immunol       Date:  2018-12-03       Impact factor: 7.561

4.  Adipose Tissue in Persons With HIV Is Enriched for CD4+ T Effector Memory and T Effector Memory RA+ Cells, Which Show Higher CD69 Expression and CD57, CX3CR1, GPR56 Co-expression With Increasing Glucose Intolerance.

Authors:  Celestine N Wanjalla; Wyatt J McDonnell; Louise Barnett; Joshua D Simmons; Briana D Furch; Morgan C Lima; Beverly O Woodward; Run Fan; Ye Fei; Paxton G Baker; Ramesh Ram; Mark A Pilkinton; Mona Mashayekhi; Nancy J Brown; Simon A Mallal; Spyros A Kalams; John R Koethe
Journal:  Front Immunol       Date:  2019-03-19       Impact factor: 7.561

Review 5.  Specific Biological Features of Adipose Tissue, and Their Impact on HIV Persistence.

Authors:  Christine Bourgeois; Jennifer Gorwood; Aurélie Barrail-Tran; Claire Lagathu; Jacqueline Capeau; Delphine Desjardins; Roger Le Grand; Abderaouf Damouche; Véronique Béréziat; Olivier Lambotte
Journal:  Front Microbiol       Date:  2019-12-17       Impact factor: 5.640

6.  TLR7 agonist, N6-LS and PGT121 delayed viral rebound in SHIV-infected macaques after antiretroviral therapy interruption.

Authors:  Denise C Hsu; Alexandra Schuetz; Rawiwan Imerbsin; Decha Silsorn; Amarendra Pegu; Dutsadee Inthawong; Jumpol Sopanaporn; Pornsuk Visudhiphan; Weerawan Chuenarom; Boot Keawboon; Wei Shi; Merlin L Robb; John R Mascola; Romas Geleziunas; Richard A Koup; Dan H Barouch; Nelson L Michael; Sandhya Vasan
Journal:  PLoS Pathog       Date:  2021-02-18       Impact factor: 6.823
  6 in total

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