Nagwa Essa1, Sara Awad2, Mariam Nashaat1. 1. Department of Dermatology and Venereology, Assiut University Hospital, Assiut, 71526, Egypt. 2. Department of Dermatology and Venereology, Assiut University Hospital, Assiut, 71526, Egypt. saramawad@gmail.com.
Abstract
PURPOSE: To translate and cross-culturally adapt the Skindex-16, a brief skin-disease-specific QoL questionnaire, into Arabic for Egyptians and to evaluate its measurement properties in Egyptian patients with skin disease. METHOD: Translation and cultural adaption were performed following guidelines for cross-cultural adaption of health-related quality of life measures. Subsequently, Skindex-16 was administered to 500 consecutive dermatological patients and 500 healthy persons for verification of its reliability and validity. Next, we examined the effect of skin disorders on QoL as well as influences of age, sex, socioeconomic level, education, and use of medication on skin disease-related QoL. RESULTS: The instrument showed high internal consistency reliability and good construct and content validity. The quality of life was most deteriorated in the emotional domain followed by symptoms domain (mean percentage score 55.5 ± 23.1 and 31.7 ± 26.8 respectively), while functioning was the least affected domain (mean percentage score 29.1 ± 26.8). Higher total Skindex-16 scores were observed for patients with psoriasis, urticaria, acne, and atopic dermatitis than those with vitiligo and alopecia areata. Educational level, social class, medication use, and family history influenced the impact of skin disease on overall QoL. CONCLUSION: The adapted Egyptian Arabic version of Skindex-16 is valid and reliable; it showed that skin problems had a clinically significant impact on QoL in Egyptian patients.
PURPOSE: To translate and cross-culturally adapt the Skindex-16, a brief skin-disease-specific QoL questionnaire, into Arabic for Egyptians and to evaluate its measurement properties in Egyptian patients with skin disease. METHOD: Translation and cultural adaption were performed following guidelines for cross-cultural adaption of health-related quality of life measures. Subsequently, Skindex-16 was administered to 500 consecutive dermatological patients and 500 healthy persons for verification of its reliability and validity. Next, we examined the effect of skin disorders on QoL as well as influences of age, sex, socioeconomic level, education, and use of medication on skin disease-related QoL. RESULTS: The instrument showed high internal consistency reliability and good construct and content validity. The quality of life was most deteriorated in the emotional domain followed by symptoms domain (mean percentage score 55.5 ± 23.1 and 31.7 ± 26.8 respectively), while functioning was the least affected domain (mean percentage score 29.1 ± 26.8). Higher total Skindex-16 scores were observed for patients with psoriasis, urticaria, acne, and atopic dermatitis than those with vitiligo and alopecia areata. Educational level, social class, medication use, and family history influenced the impact of skin disease on overall QoL. CONCLUSION: The adapted Egyptian Arabic version of Skindex-16 is valid and reliable; it showed that skin problems had a clinically significant impact on QoL in Egyptian patients.
Entities:
Keywords:
Egyptian version; Quality of life; Skin diseases; Skindex-16
Authors: Lidwine B Mokkink; Caroline B Terwee; Donald L Patrick; Jordi Alonso; Paul W Stratford; Dirk L Knol; Lex M Bouter; Henrica C W de Vet Journal: Qual Life Res Date: 2010-02-19 Impact factor: 4.147
Authors: Cecilia A C Prinsen; Robert Lindeboom; Mirjam A G Sprangers; Catharina M Legierse; John de Korte Journal: J Invest Dermatol Date: 2009-12-24 Impact factor: 8.551
Authors: Mostafa A Abolfotouh; Mohammad S Al-Khowailed; Wijdan E Suliman; Deema A Al-Turaif; Eman Al-Bluwi; Hassan S Al-Kahtani Journal: Int J Gen Med Date: 2012-07-24
Authors: Zehui He; Chuanjian Lu; Mary-Margaret Chren; Zhongzhao Zhang; Yan Li; Xiaojia Ni; Henry A Buchtel V; Paul F Ryan; Guo-Zheng Li Journal: Health Qual Life Outcomes Date: 2014-12-24 Impact factor: 3.186
Authors: Khaled Ezzedine; Viktoria Eleftheriadou; Heather Jones; Kristen Bibeau; Fiona I Kuo; Daniel Sturm; Amit G Pandya Journal: Am J Clin Dermatol Date: 2021-09-23 Impact factor: 7.403
Authors: April W Armstrong; Adam R Ford; Cindy J Chambers; Emanual Maverakis; Cory A Dunnick; Mary-Margaret Chren; Joel M Gelfand; Caitlin M Gibbons; Brittany M Gibbons; Christianne J Lane Journal: J Invest Dermatol Date: 2018-11-24 Impact factor: 8.551