Literature DB >> 28746021

Use of a Technetium99m-Sestamibi Scan to Detect Ipsilateral Double Adenoma in a Patient with Primary Hyperparathyroidism: A Case Report.

Joseph Gabriel Gabriel1, Alejandro Contreras2, Andrew Rosenthal3.   

Abstract

INTRODUCTION: Patients with primary hyperparathyroidism generally have a single parathyroid adenoma that causes excessive excretion of parathyroid hormone. For about 2% to 15% of these patients, a double adenoma is present that involves one lesion on each side of the neck. CASE
PRESENTATION: We describe a case of double parathyroid adenoma causing asymptomatic hypercalcemia. A presurgical technetium99m (Tc99m) sestamibi scan suggested an ipsilateral double adenoma in the left thyroid lobe. An intraoperative parathyroid hormone assay confirmed its successful removal. DISCUSSION: Although double adenomas are not yet widely acknowledged, presurgical imaging and nuclear scans can help to localize multiple lesions, and intraoperative parathyroid hormone assays can confirm the diagnosis and cure.

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Year:  2017        PMID: 28746021      PMCID: PMC5528857          DOI: 10.7812/TPP/16-185

Source DB:  PubMed          Journal:  Perm J        ISSN: 1552-5767


  6 in total

1.  Six hundred fifty-six consecutive explorations for primary hyperparathyroidism.

Authors:  Robert Udelsman
Journal:  Ann Surg       Date:  2002-05       Impact factor: 12.969

2.  A quick intraoperative parathyroid hormone assay in the surgical management of patients with primary hyperparathyroidism: a study of 206 consecutive cases.

Authors:  E Vignali; A Picone; G Materazzi; S Steffe; P Berti; L Cianferotti; F Cetani; E Ambrogini; P Miccoli; A Pinchera; C Marcocci
Journal:  Eur J Endocrinol       Date:  2002-06       Impact factor: 6.664

Review 3.  Clinical practice. Primary hyperparathyroidism.

Authors:  Claudio Marcocci; Filomena Cetani
Journal:  N Engl J Med       Date:  2011-12-22       Impact factor: 91.245

4.  Intraoperative parathyroid hormone assay in patients with primary hyperparathyroidism and double adenoma.

Authors:  Emad Kandil; Haytham H Alabbas; Anshuman Bansal; Tareq Islam; Anthony P Tufaro; Ralph P Tufano
Journal:  Arch Otolaryngol Head Neck Surg       Date:  2009-12

5.  Does intraoperative quick parathyroid hormone assay improve the results of parathyroidectomy?

Authors:  Daishu Miura; Nobuyuki Wada; Cumhur Arici; Eugene Morita; Quan-Yang Duh; Orlo H Clark
Journal:  World J Surg       Date:  2002-04-30       Impact factor: 3.352

6.  Intraoperative PTH Assay during Minimally Invasive Parathyroidectomy May Be Helpful in the Detection of Double Adenomas and May Minimise the Risk of Recurrent Surgery.

Authors:  E Ypsilantis; H Charfare; W S Wassif
Journal:  Int J Endocrinol       Date:  2010-12-15       Impact factor: 3.257

  6 in total

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