| Literature DB >> 28744634 |
I I Zamorskii1, T S Shchudrova1, N S Lin'kova2,3, T E Nichik4, V Kh Khavinson4,5.
Abstract
EDL peptide produced a nephroprotective effect on experimental models gentamycin-induced nephropathy and ischemia/reperfusion kidney injury in rats. The nephroprotective effect of EDL peptide manifested in prevention of oliguria and retention azotemia, a decrease in proteinuria and sodium excretion, prevention of critical decrease in activities of antioxidant enzymes, suppression of LPO, and normalization of energy supply to kidneys cells. Our findings confirm the prospects of further studies of the nephroprotective properties of peptide EDL in various pathologies of the kidneys.Entities:
Keywords: EDL peptide; acute kidney damage injury; nephroprotection
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Year: 2017 PMID： 28744634 DOI： 10.1007/s10517-017-3811-1
Source DB: PubMed Journal: Bull Exp Biol Med ISSN： 0007-4888 Impact factor: 0.804