Literature DB >> 28743171

A quantified risk-scoring system and rating model for postsurgical gastroparesis syndrome in gastric cancer patients.

Xiao-Dong Chen1, Chen-Chen Mao1, Wei-Teng Zhang1, Ji Lin1, Rui-Sen Wu1, Feng-Min Zhang1, Xiang-Wei Sun1, Chu-Huai Chi1, Xian Shen1,2, Peng-Fei Wang1.   

Abstract

BACKGROUND AND OBJECTIVES: The study aimed to investigate the relationship between obesity and postsurgical gastroparesis syndrome (PGS), and to construct a scoring system and a risk model to identify patients at high risk.
METHODS: A total of 634 patients were retrospectively analyzed. Clinical characteristics were evaluated via receiver operating characteristic (ROC) curve analysis. Logistic analysis was performed to determine the independent predictive indicators of PGS. A scoring system consisting of these indicators and a risk-rating model were constructed and evaluated via ROC curve analysis.
RESULTS: Based on the ROC curves, the visceral fat area (VFA) cutoff value for PGS was 94.00. Logistic analysis showed that visceral obesity (VFA ≥ 94.00 cm2 ), the reconstruction technique, and tumor size were independent prognostic factors for PGS. The scoring system could predict PGS reliably with a high area under the ROC curve ([AUC] = 0.769). A high-risk rating had a high AUC (AUC I = 0.56, AUC II = 0.65, and AUC III = 0.77), indicating that the risk-rating model could effectively screen patients at high risk of PGS.
CONCLUSIONS: Visceral obesity defined by VFA effectively predicted PGS. Our scoring system may be a reliable instrument for identifying patients most at risk of PGS.
© 2017 Wiley Periodicals, Inc.

Entities:  

Keywords:  postsurgical gastroparesis syndrome; risk model; scoring system; visceral obesity

Mesh:

Year:  2017        PMID: 28743171     DOI: 10.1002/jso.24691

Source DB:  PubMed          Journal:  J Surg Oncol        ISSN: 0022-4790            Impact factor:   3.454


  4 in total

1.  Value of Visceral Fat Area in the Preoperative Discrimination of Peritoneal Metastasis from Gastric Cancer in Patients with Different Body Mass Index: A Prospective Study.

Authors:  He Huang; Xinxin Yang; Jing Sun; Ce Zhu; Xiang Wang; Yunpeng Zeng; Jingxuan Xu; Chenchen Mao; Xian Shen
Journal:  Cancer Manag Res       Date:  2020-07-28       Impact factor: 3.989

2.  Preoperative Blood Glucose Level Predicts Postsurgical Gastroparesis Syndrome after Subtotal Gastrectomy: Development of an Individualized Usable Nomogram.

Authors:  Chenchen Mao; Xin Liu; Yunshi Huang; Mingming Shi; Weiyang Meng; Libin Xu; Weisheng Chen; Yuanbo Hu; Xinxin Yang; Xiaodong Chen; Xian Shen
Journal:  J Diabetes Res       Date:  2020-05-14       Impact factor: 4.011

3.  Laparoscopic gastrectomy reduces adverse postoperative outcomes and decreases morbidity for gastric cancer patients with visceral obesity: a propensity score-matched analysis.

Authors:  Chenchen Mao; Xiaodong Chen; Xiangwei Sun; Xiang Wang; Ce Zhu; Wenjing Chen; Xiangyang Xue; Xian Shen
Journal:  J Cancer       Date:  2021-02-21       Impact factor: 4.207

4.  Short-term surgical outcomes of laparoscopy-assisted versus open D2 distal gastrectomy for locally advanced gastric cancer in North China: a multicenter randomized controlled trial.

Authors:  Zaozao Wang; Jiadi Xing; Jun Cai; Zhongtao Zhang; Fei Li; Nengwei Zhang; Jixiang Wu; Ming Cui; Ying Liu; Lei Chen; Hong Yang; Zhi Zheng; Xiaohui Wang; Chongchong Gao; Zhe Wang; Qing Fan; Yanlei Zhu; Shulin Ren; Chenghai Zhang; Maoxing Liu; Jiafu Ji; Xiangqian Su
Journal:  Surg Endosc       Date:  2018-11-01       Impact factor: 4.584

  4 in total

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