| Literature DB >> 28741524 |
Abstract
The interplay between cancer cells and stromal cells is increasingly recognized as a main driver of tumor progression and metastasis. This Forum article highlights the role of cancer-associated stromal fibroblasts (CAFs) in tumorigenesis and discusses the potential for developing specific stromal cancer therapies.Entities:
Keywords: cancer therapy; cancer-associated fibroblasts; exosomes; miRNA; tumor stroma
Mesh:
Year: 2016 PMID: 28741524 DOI: 10.1016/j.trecan.2016.04.005
Source DB: PubMed Journal: Trends Cancer ISSN: 2405-8025