Literature DB >> 28741524

Cancer-Associated Fibroblasts: Perspectives in Cancer Therapy.

Jai Prakash1.   

Abstract

The interplay between cancer cells and stromal cells is increasingly recognized as a main driver of tumor progression and metastasis. This Forum article highlights the role of cancer-associated stromal fibroblasts (CAFs) in tumorigenesis and discusses the potential for developing specific stromal cancer therapies.
Copyright © 2016 Elsevier Inc. All rights reserved.

Entities:  

Keywords:  cancer therapy; cancer-associated fibroblasts; exosomes; miRNA; tumor stroma

Mesh:

Year:  2016        PMID: 28741524     DOI: 10.1016/j.trecan.2016.04.005

Source DB:  PubMed          Journal:  Trends Cancer        ISSN: 2405-8025


  23 in total

Review 1.  Nanomaterial-Based Modulation of Tumor Microenvironments for Enhancing Chemo/Immunotherapy.

Authors:  Quoc-Viet Le; Juhan Suh; Yu-Kyoung Oh
Journal:  AAPS J       Date:  2019-05-17       Impact factor: 4.009

Review 2.  Advancing Tumor Microenvironment Research by Combining Organs-on-Chips and Biosensors.

Authors:  Isabel Calejo; Marcel Alexander Heinrich; Giorgia Zambito; Laura Mezzanotte; Jai Prakash; Liliana Moreira Teixeira
Journal:  Adv Exp Med Biol       Date:  2022       Impact factor: 3.650

3.  PDGFR-β+ fibroblasts deteriorate survival in human solid tumors: a meta-analysis.

Authors:  Guoming Hu; Liming Huang; Kefang Zhong; Liwei Meng; Feng Xu; Shimin Wang; Tao Zhang
Journal:  Aging (Albany NY)       Date:  2021-05-03       Impact factor: 5.682

4.  Persistent DNA strand breaks induce a CAF-like phenotype in normal fibroblasts.

Authors:  Arnaud J Legrand; Mattia Poletto; Daniela Pankova; Elena Clementi; John Moore; Francesc Castro-Giner; Anderson J Ryan; Eric O'Neill; Enni Markkanen; Grigory L Dianov
Journal:  Oncotarget       Date:  2018-02-07

Review 5.  Cancer-associated fibroblasts as abettors of tumor progression at the crossroads of EMT and therapy resistance.

Authors:  Micol Eleonora Fiori; Simone Di Franco; Lidia Villanova; Paola Bianca; Giorgio Stassi; Ruggero De Maria
Journal:  Mol Cancer       Date:  2019-03-30       Impact factor: 27.401

6.  Proteomic Profiling of Human Prostate Cancer-associated Fibroblasts (CAF) Reveals LOXL2-dependent Regulation of the Tumor Microenvironment.

Authors:  Elizabeth V Nguyen; Brooke A Pereira; Mitchell G Lawrence; Xiuquan Ma; Richard J Rebello; Howard Chan; Birunthi Niranjan; Yunjian Wu; Stuart Ellem; Xiaoqing Guan; Jianmin Wu; Joanna N Skhinas; Thomas R Cox; Gail P Risbridger; Renea A Taylor; Natalie L Lister; Roger J Daly
Journal:  Mol Cell Proteomics       Date:  2019-05-06       Impact factor: 5.911

7.  Carcinoma-associated fibroblasts derived exosomes modulate breast cancer cell stemness through exonic circHIF1A by miR-580-5p in hypoxic stress.

Authors:  Yanxia Zhan; Junxian Du; Zhihui Min; Li Ma; Wei Zhang; Wei Zhu; Yonglei Liu
Journal:  Cell Death Discov       Date:  2021-06-12

8.  Carcinoma associated fibroblasts small extracellular vesicles with low miR-7641 promotes breast cancer stemness and glycolysis by HIF-1α.

Authors:  Yonglei Liu; Fanli Hua; Yanxia Zhan; Yanfei Yang; Jianfang Xie; Yunfeng Cheng; Feng Li
Journal:  Cell Death Discov       Date:  2021-07-08

Review 9.  Pancreatic Cancer Associated Fibroblasts (CAF): Under-Explored Target for Pancreatic Cancer Treatment.

Authors:  Jeffrey Norton; Deshka Foster; Malini Chinta; Ashley Titan; Michael Longaker
Journal:  Cancers (Basel)       Date:  2020-05-25       Impact factor: 6.639

Review 10.  Perspective: bidirectional exosomal transport between cancer stem cells and their fibroblast-rich microenvironment during metastasis formation.

Authors:  Gábor Valcz; Edit Irén Buzás; Zoltán Szállási; Alexandra Kalmár; Tibor Krenács; Zsolt Tulassay; Péter Igaz; Béla Molnár
Journal:  NPJ Breast Cancer       Date:  2018-07-16
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