Literature DB >> 28740777

Prepectoral Breast Reconstruction or Muscle-Sparing Technique with the Braxon Porcine Acellular Dermal Matrix.

Raghavan Vidya1.   

Abstract

Supplemental Digital Content is available in the text.

Entities:  

Year:  2017        PMID: 28740777      PMCID: PMC5505838          DOI: 10.1097/GOX.0000000000001364

Source DB:  PubMed          Journal:  Plast Reconstr Surg Glob Open        ISSN: 2169-7574


INTRODUCTION

Implant-based breast reconstruction is on the rise and the use of meshes have facilitated adoption of novel techniques.[1] The disadvantages related to traditional submuscular reconstruction had led to adoption of muscle sparing or prepectoral technique.[2]

INDICATIONS AND PATIENT SELECTION

It is primarily used in immediate breast reconstruction and in revision surgery. Appropriate selection of patients, tumour biology, and technique are important.[3]

TECHNIQUE

Braxon 30 × 20 cm (Decomed S.r.l., Venezia, Italy) is the only preshaped porcine-derived acelular dermal matrix (ADM) matrix that is available[2] (see videos, Supplemental Digital Contents 1–3, which describe the prepectoral technique using braxon preshaped ADM step by step. These videos are available in the Related Videos section of the Full-Text article on PRSGlobalOpen.com or available at http://links.lww.com/PRSGO/A460, http://links.lww.com/PRSGO/A461, and http://links.lww.com/PRSGO/A462). It is 0.6-mm thick, packed dry, and need to be hydrated in saline, so it becomes soft after hydration. It has an anterior flap with a central slit, which when sutured gives the shape. The posterior flap with 2 windows, which is believed, let the seroma fluid out so as to avoid any collection inside the new pocket. The anterior slit and the 2 wings are closed using 2-0 vicryl continuous suture. The desired implant is then placed inside the ADM. A marking pen is used to define the exact size of the matrix that is required to form a wrap around the implant so that the ADM snugs the implant and there is no redundant space inside. It is also useful to leave a 2-mm rim around the edges, which will enable easy anchorage to the chest wall. The anterior and posterior edges of the device are sutured together using 2-0 vicryl to form a pocket for the implant. The inferior aspect of Braxon provides the required ptosis and does not require any anchorage. The lateral space can be closed to improve the shape and reduce any dead space. The new reconstructed ADM implant unit is placed over the prepectoral space and anchored to the muscle using cardinal sutures at 3, 6, 9, and 12-clock positions using 2-0 vicryl sutures. Other sutures can be placed especially laterally and anteriorly between the matrix and subcutaneous layer before the closure of the skin. All these suture stitches speed up the process of matrix integration and, on the other side, decrease the mechanical stress of the breast implant on the lower pole by suspending the silicone weight. The wound is closed using 3-0 vicryl, and a drain is used.

OUTCOME

The recent prospective, multicenter study using Braxon in 100 cases (median follow-up, 17.9 months) showed 2% implant loss, 1% wound breakdown, 5% seroma, and 2% haematoma.[4] Problems such as animation deformity and shoulder dysfunction are avoided, and postoperative pain and physiotherapy are minimal due to preservation of chest wall. It appears to be preferred in young, athletic women and in those who prefer to undisturb the chest wall musculature. Rarely, some very thin patients may develop a visible rim of the implant in the upper pole, which can be corrected by lipomodeling as shown by Becker et al.[5] (6.4%) in his series.

CONCLUSIONS

The novel wrap around muscle sparing technique adds a whole new dimension to breast reconstruction. See video, Supplemental Digital Content 1, which demonstrates the prepectoral technique using braxon preshaped ADM step by step. This is Part 1. This video is available in the Related Videos section of the Full-Text article on PRSGlobalOpen.com or available at http://links.lww.com/PRSGO/A460. See video, Supplemental Digital Content 2, which demonstrates the prepectoral technique using braxon preshaped ADM step by step. This is Part 2. This video is available in the Related Videos section of the Full-Text article on PRSGlobalOpen.com or available at http://links.lww.com/PRSGO/A461. See video, Supplemental Digital Content 3, which demonstrates the prepectoral technique using braxon preshaped ADM step by step. This is Part 3. This video is available in the Related Videos section of the Full-Text article on PRSGlobalOpen.com or available at http://links.lww.com/PRSGO/A462.
  4 in total

Review 1.  Acellular dermis-assisted prosthetic breast reconstruction: a systematic and critical review of efficacy and associated morbidity.

Authors:  Hani Sbitany; Joseph M Serletti
Journal:  Plast Reconstr Surg       Date:  2011-12       Impact factor: 4.730

2.  Evaluation of a novel breast reconstruction technique using the Braxon® acellular dermal matrix: a new muscle-sparing breast reconstruction.

Authors:  Giorgio Berna; Simon J Cawthorn; Guido Papaccio; Nicola Balestrieri
Journal:  ANZ J Surg       Date:  2014-09-29       Impact factor: 1.872

3.  Evaluation of the effectiveness of the prepectoral breast reconstruction with Braxon dermal matrix: First multicenter European report on 100 cases.

Authors:  Raghavan Vidya; Jaume Masià; Simon Cawthorn; Giorgio Berna; Fernando Bozza; Alexander Gardetto; Agnieszka Kołacińska; Francesco Dell'Antonia; Cesare Tiengo; Franco Bassetto; Glenda G Caputo; Maurizio Governa
Journal:  Breast J       Date:  2017-05-08       Impact factor: 2.431

4.  Immediate Implant-based Prepectoral Breast Reconstruction Using a Vertical Incision.

Authors:  Hilton Becker; Jeffrey G Lind; Elizabeth G Hopkins
Journal:  Plast Reconstr Surg Glob Open       Date:  2015-07-08
  4 in total
  9 in total

1.  Selective pectoralis major muscle denervation in breast reconstruction: a technical modification for more effective and cosmetic results.

Authors:  Marco Bernini; Donato Casella; Carlo Mariotti
Journal:  Gland Surg       Date:  2017-12

Review 2.  Strategies and considerations in selecting between subpectoral and prepectoral breast reconstruction.

Authors:  Ara A Salibian; Jordan D Frey; Nolan S Karp
Journal:  Gland Surg       Date:  2019-02

3.  Pre-pectoral breast reconstruction: early and long-term safety evaluation of 146 unselected cases of the early pre-pectoral era of a single-institution, including cases with previous breast irradiation and post-mastectomy radiation therapy.

Authors:  Marco Bernini; Icro Meattini; Calogero Saieva; Carlotta Becherini; Viola Salvestrini; Luca Visani; Giulia Stocchi; Chiara Bellini; Victoria Lorenzetti; Silvia Sordi; Jacopo Nori; Diego De Benedetto; Isacco Desideri; Simonetta Bianchi; Lorenzo Livi; Lorenzo Orzalesi
Journal:  Breast Cancer       Date:  2021-11-14       Impact factor: 4.239

4.  Single stage, direct to implant pre-pectoral breast reconstruction.

Authors:  Glyn Jones; Anuja K Antony
Journal:  Gland Surg       Date:  2019-02

5.  Technique Refinement in Prepectoral Implant Breast Reconstruction with Vicryl Mesh Pocket and Acellular Dermal Matrix Support.

Authors:  Lisa Gfrerer; Eric C Liao
Journal:  Plast Reconstr Surg Glob Open       Date:  2018-04-09

6.  Ischemic Complications after Nipple-sparing Mastectomy: Predictors of Reconstructive Failure in Implant-based Reconstruction and Implications for Decision-making.

Authors:  Ara A Salibian; Jordan D Frey; Jonathan M Bekisz; Nolan S Karp; Mihye Choi
Journal:  Plast Reconstr Surg Glob Open       Date:  2019-05-23

7.  Novel three-dimensional acellular dermal matrix for prepectoral breast reconstruction: First year in review with BRAXON® Fast.

Authors:  Giorgio Berna; Alessia De Grazia; Elisa Antoniazzi; Marco Romeo; Francesco Dell'Antonia; Stefano Lovero; Paolo Marchica; Christian Rizzetto; Paolo Burelli
Journal:  Front Surg       Date:  2022-09-05

8.  Rippling Associated with Pre-Pectoral Implant Based Breast Reconstruction: A New Grading System.

Authors:  Raghavan Vidya; Fahad Mujtaba Iqbal; Hilton Becker; Olga Zhadan
Journal:  World J Plast Surg       Date:  2019-09

9.  The largest multicentre data collection on prepectoral breast reconstruction: The iBAG study.

Authors:  Jaume Masià
Journal:  J Surg Oncol       Date:  2020-08-12       Impact factor: 3.454

  9 in total

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