Literature DB >> 28740536

LoCa LoPa myelopathy: is prevention better than cure?

Kamal Kishore Pandita1, Sushil Razdan2, Sarla Pandita3.   

Abstract

Manifestations of primary hypoparathyroidism are produced by neuromuscular irritability or by extraosseous calcifications. We present a patient of primary hypoparathyroidism who had extensive calcification of brain parenchyma, and was suffering from chronic, generalised and progressive stiffness of body due to cervical compressive myelopathy, caused by calcification of posterior longitudinal ligament and ligamentum flavum. By presenting this case we wanted to emphasize the usefulness of meticulous clinical examination to differentiate the stiffness caused by myelopathy from that which is caused by possible coexisting extrapyramidal disorder. This case presentation also builds the hypothesis that early diagnosis and institution of early and appropriate treatment has potential to prevent the complications arising from extraosseous calcifications in patients with primary hypoparathyroidism.

Entities:  

Keywords:  extraosseous calcification; hypoparathyroidism; myelopathy

Year:  2017        PMID: 28740536      PMCID: PMC5505706          DOI: 10.11138/ccmbm/2017.14.1.105

Source DB:  PubMed          Journal:  Clin Cases Miner Bone Metab        ISSN: 1724-8914


  4 in total

Review 1.  A rare case of idiopathic hypoparathyroidism with varied neurological manifestations.

Authors:  S Abe; K Tojo; K Ichida; T Shigematsu; T Hasegawa; M Morita; O Sakai
Journal:  Intern Med       Date:  1996-02       Impact factor: 1.271

2.  European Society of Endocrinology Clinical Guideline: Treatment of chronic hypoparathyroidism in adults.

Authors:  Jens Bollerslev; Lars Rejnmark; Claudio Marcocci; Dolores M Shoback; Antonio Sitges-Serra; Wim van Biesen; Olaf M Dekkers
Journal:  Eur J Endocrinol       Date:  2015-08       Impact factor: 6.664

3.  Spectrum of neurological manifestations of idiopathic hypoparathyroidism and pseudohypoparathyroidism.

Authors:  Sanjay Kumar Bhadada; Anil Bhansali; Vimal Upreti; Sridhar Subbiah; Niranjan Khandelwal
Journal:  Neurol India       Date:  2011 Jul-Aug       Impact factor: 2.117

4.  Undetected hypoparathyroidism: An unusual cause of perioperative morbidity.

Authors:  Ashish Chakravarty; Saurabh Anand; Harsh Sapra; Yatin Mehta
Journal:  Indian J Anaesth       Date:  2014-07
  4 in total

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