Literature DB >> 28740532

Is this a seizure?

Giulio Franceschet1, Marta Mazzucato1, Simona Censi1, Stefano Simmini1, Marco Boscaro1, Valentina Camozzi1.   

Abstract

We describe a case of a 65-year-old woman admitted to the hospital for suspected of epileptic crisis. She was affected by diabetes and hiatal hernia for which she was taking Proton Pump Inhibitors (PPIs) for about 8 years. She showed hypocalcaemia, hypomagnesaemia, hyperparathyroidism and severe hypovitaminosis D. We exclude malabsorption and magnesium loss. After restored vitamin D levels, stopped use of PPI, start calcium and magnesium supplementation normal values of the ions were restored. This case underlies the importance of evaluate magnesium routinely, other than calcium and vitamin D, and use PPI more carefully.

Entities:  

Keywords:  hypocalcaemia; hypoparathyroidism; magnesium; protom pump inhibitors

Year:  2017        PMID: 28740532      PMCID: PMC5505721          DOI: 10.11138/ccmbm/2017.14.1.089

Source DB:  PubMed          Journal:  Clin Cases Miner Bone Metab        ISSN: 1724-8914


  7 in total

1.  Proton-pump inhibitors and hypomagnesemic hypoparathyroidism.

Authors:  Martin Epstein; Shaun McGrath; Florence Law
Journal:  N Engl J Med       Date:  2006-10-26       Impact factor: 91.245

2.  Paradoxical block of parathormone secretion is mediated by increased activity of G alpha subunits.

Authors:  U Quitterer; M Hoffmann; M Freichel; M J Lohse
Journal:  J Biol Chem       Date:  2000-12-01       Impact factor: 5.157

Review 3.  Proton-pump inhibitor-induced hypomagnesemia: Current research and proposed mechanisms.

Authors:  Jeffrey H William; John Danziger
Journal:  World J Nephrol       Date:  2016-03-06

4.  Bartter and Gitelman syndromes: Spectrum of clinical manifestations caused by different mutations.

Authors:  Amar Al Shibli; Hassib Narchi
Journal:  World J Methodol       Date:  2015-06-26

5.  Proton pump inhibitors and hypomagnesemia in the general population: a population-based cohort study.

Authors:  Brenda C T Kieboom; Jessica C Kiefte-de Jong; Mark Eijgelsheim; Oscar H Franco; Ernst J Kuipers; Albert Hofman; Robert Zietse; Bruno H Stricker; Ewout J Hoorn
Journal:  Am J Kidney Dis       Date:  2015-06-26       Impact factor: 8.860

Review 6.  Proton pump inhibitor-associated hypomagnesemia: what do FDA data tell us?

Authors:  Chee Phun Luk; Richard Parsons; Ya Ping Lee; Jeffery David Hughes
Journal:  Ann Pharmacother       Date:  2013-04-30       Impact factor: 3.154

7.  Hypomagnesaemia associated with long-term use of proton pump inhibitors.

Authors:  James Wei Tatt Toh; Evonne Ong; Robert Wilson
Journal:  Gastroenterol Rep (Oxf)       Date:  2014-08-19
  7 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.