Literature DB >> 2874001

Stereoselective oxidative metabolism of propranolol in the microsomal fraction from rat and human liver. Use of deuterium labeling and pseudoracemic mixtures.

W L Nelson, H U Shetty.   

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Year:  1986        PMID： 2874001

Source DB:  PubMed          Journal:  Drug Metab Dispos        ISSN： 0090-9556            Impact factor:   3.922


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  4 in total

1.  Propranolol oxidation by human liver microsomes--the use of cumene hydroperoxide to probe isoenzyme specificity and regio- and stereoselectivity.

Authors:  S V Otton; E M Gillam; M S Lennard; G T Tucker; H F Woods
Journal:  Br J Clin Pharmacol       Date:  1990-11       Impact factor: 4.335

2.  Identification of human CYP isoforms involved in the metabolism of propranolol enantiomers--N-desisopropylation is mediated mainly by CYP1A2.

Authors:  K Yoshimoto; H Echizen; K Chiba; M Tani; T Ishizaki
Journal:  Br J Clin Pharmacol       Date:  1995-04       Impact factor: 4.335

3.  Selective effect of adjuvant arthritis on the disposition of propranolol enantiomers in rats detected using a stereospecific HPLC assay.

Authors:  M Piquette-Miller; F Jamali
Journal:  Pharm Res       Date:  1993-02       Impact factor: 4.200

4.  Site- and stereospecific ocular drug delivery by sequential enzymatic bioactivation.

Authors:  N Bodor; L Prokai
Journal:  Pharm Res       Date:  1990-07       Impact factor: 4.200
  4 in total

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