Literature DB >> 28737793

Asymmetric synthesis of isoquinolinonaphthyridines catalyzed by a chiral Brønsted acid.

Jianjun Li1, Yiwei Fu, Cong Qin, Yang Yu, Hao Li, Wei Wang.   

Abstract

A catalytic asymmetric method for the synthesis of chiral isoquinolinonaphthyridines has been developed. A chiral disulfonimide catalyzes a redox cyclization reaction between 2-methyl-3-aldehydeazaarenes and 1,2,3,4-tetrahydroisoquinolines to deliver a range of isoquinolinonaphthyridines with good to high yields (up to 91%) and up to 92 : 8 er.

Entities:  

Year:  2017        PMID： 28737793     DOI： 10.1039/c7ob01527e

Source DB:  PubMed          Journal:  Org Biomol Chem        ISSN： 1477-0520            Impact factor:   3.876


  8 in total

1.  Redox-Annulations of Cyclic Amines with ortho-Cyanomethylbenzaldehydes.

Authors:  Anirudra Paul; Hemant S Chandak; Longle Ma; Daniel Seidel
Journal:  Org Lett       Date:  2020-01-27       Impact factor: 6.005

2.  Redox-Annulations of Cyclic Amines with Electron-Deficient o-Tolualdehydes.

Authors:  Anirudra Paul; Alafate Adili; Daniel Seidel
Journal:  Org Lett       Date:  2019-03-06       Impact factor: 6.005

3.  Condensation-Based Methods for the C-H Bond Functionalization of Amines.

Authors:  Weijie Chen; Daniel Seidel
Journal:  Synthesis (Stuttg)       Date:  2021-09-02       Impact factor: 3.157

4.  Redox-Annulations of Cyclic Amines with 2-(2-Oxoethyl)malonates.

Authors:  Zhengbo Zhu; Hemant S Chandak; Daniel Seidel
Journal:  Org Lett       Date:  2018-06-25       Impact factor: 6.005

5.  α-C-H/N-H Annulation of Alicyclic Amines via Transient Imines: Preparation of Polycyclic Lactams.

Authors:  Weijie Chen; Daniel Seidel
Journal:  Org Lett       Date:  2021-04-21       Impact factor: 6.005

6.  Synthesis of Polycyclic Isoindolines via α-C-H/N-H Annulation of Alicyclic Amines.

Authors:  Anirudra Paul; Camille Vasseur; Scott D Daniel; Daniel Seidel
Journal:  Org Lett       Date:  2022-01-31       Impact factor: 6.072

7.  Synthesis of Polycyclic Imidazolidinones via Amine Redox-Annulation.

Authors:  Zhengbo Zhu; Xin Lv; Jason E Anesini; Daniel Seidel
Journal:  Org Lett       Date:  2017-11-16       Impact factor: 6.005

8.  Traceless Redox-Annulations of Alicyclic Amines.

Authors:  Dillon R L Rickertsen; Longle Ma; Anirudra Paul; Khalil A Abboud; Daniel Seidel
Journal:  SynOpen       Date:  2020-12-16
  8 in total

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