R Ambrus1, L B Svendsen1, N H Secher2, J P Goetze3, K Rünitz2, M P Achiam1. 1. 1 Department of Surgical Gastroenterology, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark. 2. 2 Department of Anesthesiology 2041, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark. 3. 3 Department of Clinical Biochemistry, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.
Abstract
BACKGROUND: During abdominal surgery, traction of the mesenterium provokes mesenteric traction syndrome, including hypotension, tachycardia, and flushing, along with an increase in plasma prostacyclin (PGI2). We evaluated whether postoperative complications are related to mesenteric traction syndrome during esophagectomy. METHODS: Flushing, hemodynamic variables, and plasma 6-keto-PGF1α were recorded during the abdominal part of open ( n = 25) and robotically assisted ( n = 25) esophagectomy. Postoperative complications were also registered, according to the Clavien-Dindo classification. RESULTS: Flushing appeared in 17 (open) and 5 (robotically assisted) surgical cases ( p = 0.001). Mean arterial pressure was stable during both types of surgeries, but infusion of vasopressors during the first hour of open surgery was related to development of widespread (Grade II) flushing ( p = 0.036). For patients who developed flushing, heart rate and plasma 6-keto-PGF1α also increased ( p = 0.001 and p < 0.001, respectively). Furthermore, severe postoperative complications were related to Grade II flushing ( p = 0.037). CONCLUSION: Mesenteric traction syndrome manifests more frequently during open than robotically assisted esophagectomy, and postoperative complications appear to be associated with severe mesenteric traction syndrome.
BACKGROUND: During abdominal surgery, traction of the mesenterium provokes mesenteric traction syndrome, including hypotension, tachycardia, and flushing, along with an increase in plasma prostacyclin (PGI2). We evaluated whether postoperative complications are related to mesenteric traction syndrome during esophagectomy. METHODS:Flushing, hemodynamic variables, and plasma 6-keto-PGF1α were recorded during the abdominal part of open ( n = 25) and robotically assisted ( n = 25) esophagectomy. Postoperative complications were also registered, according to the Clavien-Dindo classification. RESULTS:Flushing appeared in 17 (open) and 5 (robotically assisted) surgical cases ( p = 0.001). Mean arterial pressure was stable during both types of surgeries, but infusion of vasopressors during the first hour of open surgery was related to development of widespread (Grade II) flushing ( p = 0.036). For patients who developed flushing, heart rate and plasma 6-keto-PGF1α also increased ( p = 0.001 and p < 0.001, respectively). Furthermore, severe postoperative complications were related to Grade II flushing ( p = 0.037). CONCLUSION: Mesenteric traction syndrome manifests more frequently during open than robotically assisted esophagectomy, and postoperative complications appear to be associated with severe mesenteric traction syndrome.
Authors: Linea L Ring; Rune B Strandby; Amalie Henriksen; Rikard Ambrus; Henrik Sørensen; Jens P Gøtze; Lars B Svendsen; Michael P Achiam Journal: J Clin Monit Comput Date: 2018-11-20 Impact factor: 2.502
Authors: August Adelsten Olsen; Rune Broni Strandby; Pär Ingemar Johansson; Henrik Sørensen; Lars Bo Svendsen; Michael Patrick Achiam Journal: Langenbecks Arch Surg Date: 2022-04-09 Impact factor: 2.895
Authors: August A Olsen; Rune B Strandby; Nikolaj Nerup; Rikard Ambrus; Jens Peter Gøtze; Lars Bo Svendsen; Michael P Achiam Journal: Langenbecks Arch Surg Date: 2019-12-09 Impact factor: 3.445
Authors: August Adelsten Olsen; Rune Broni Strandby; Nikolaj Nerup; Pär Ingemar Johansson; Lars Bo Svendsen; Michael Patrick Achiam Journal: Langenbecks Arch Surg Date: 2021-03-08 Impact factor: 3.445
Authors: Rune B Strandby; Rikard Ambrus; Linea L Ring; Nikolaj Nerup; Niels H Secher; Jens P Goetze; Michael P Achiam; Lars B Svendsen Journal: Local Reg Anesth Date: 2021-03-02
Authors: Rune B Strandby; Jens T F Osterkamp; Rikard Ambrus; Amelie Henriksen; Jens P Goetze; Niels H Secher; Michael P Achiam; Lars-Bo Svendsen Journal: Animal Model Exp Med Date: 2021-03-23