Hind A Beydoun1, May A Beydoun2, Xiaoli Chen3, Jen Jen Chang4, Alyssa A Gamaldo5, Shaker M Eid1, Alan B Zonderman6. 1. School of Medicine, Johns Hopkins University, Baltimore, MD, USA. 2. Intramural Research Program, National Institute on Aging, Baltimore, MD, USA. Electronic address: baydounm@mail.nih.gov. 3. Massachusetts Department of Public Health, Boston, MA, USA. 4. Saint Louis University, College of Public Health and Social Justice, Department of Epidemiology, St Louis, MO, USA. 5. Human Development and Family Studies, Pennsylvania State University, State College, PA, USA. 6. Intramural Research Program, National Institute on Aging, Baltimore, MD, USA.
Abstract
OBJECTIVE: Our aim was to examine sex- and age-specific relationships of sleep behaviors with all-cause mortality rates. METHODS: A retrospective cohort study was conducted among 5288 adults (≥50 years) from the 2005-2008 National Health and Nutrition Examination Surveys who were followed-up for 54.9 ± 1.2 months. Sleep duration was categorized as < 7 h, 7-8 h and >8 h. Two sleep quality indices were generated through factor analyses. 'Help-seeking behavior for sleep problems' and 'diagnosis with sleep disorders' were defined as yes/no questions. Sociodemographic covariates-adjusted Cox regression models were applied to estimate hazard ratios (HRs) and 95% confidence intervals (CIs). RESULTS: A positive relationship was observed between long sleep and all-cause mortality rate in the overall sample (HR = 1.90, 95% CI: 1.38, 2.60), among males (HR = 1.48, 95% CI: 1.05, 2.09), females (HR = 2.32, 95% CI: 1.48, 3.61) and elderly (≥65 years) people (HR = 1.80, 95% CI: 1.30, 2.50). 'Sleepiness/sleep disturbance' (Factor I) and all-cause mortality rate were positively associated among males (HR = 1.22, 95% CI: 1.03, 1.45), whereas 'poor sleep-related daytime dysfunction' (Factor II) and all-cause mortality (HR = 0.75, 95% CI: 0.62, 0.91) were negatively associated among elderly people. CONCLUSIONS: Sex- and age-specific relationships were observed between all-cause mortality rate and specific sleep behaviors among older adults. Published by Elsevier B.V.
OBJECTIVE: Our aim was to examine sex- and age-specific relationships of sleep behaviors with all-cause mortality rates. METHODS: A retrospective cohort study was conducted among 5288 adults (≥50 years) from the 2005-2008 National Health and Nutrition Examination Surveys who were followed-up for 54.9 ± 1.2 months. Sleep duration was categorized as < 7 h, 7-8 h and >8 h. Two sleep quality indices were generated through factor analyses. 'Help-seeking behavior for sleep problems' and 'diagnosis with sleep disorders' were defined as yes/no questions. Sociodemographic covariates-adjusted Cox regression models were applied to estimate hazard ratios (HRs) and 95% confidence intervals (CIs). RESULTS: A positive relationship was observed between long sleep and all-cause mortality rate in the overall sample (HR = 1.90, 95% CI: 1.38, 2.60), among males (HR = 1.48, 95% CI: 1.05, 2.09), females (HR = 2.32, 95% CI: 1.48, 3.61) and elderly (≥65 years) people (HR = 1.80, 95% CI: 1.30, 2.50). 'Sleepiness/sleep disturbance' (Factor I) and all-cause mortality rate were positively associated among males (HR = 1.22, 95% CI: 1.03, 1.45), whereas 'poor sleep-related daytime dysfunction' (Factor II) and all-cause mortality (HR = 0.75, 95% CI: 0.62, 0.91) were negatively associated among elderly people. CONCLUSIONS: Sex- and age-specific relationships were observed between all-cause mortality rate and specific sleep behaviors among older adults. Published by Elsevier B.V.
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